Protein Alignment Nlg3 and Ces2h

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 663
• Identity: 185/663 - (27%)
• Similarity: 273/663 - (41%)
• Gaps: 151/663 - (22%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLD-PVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFS 217
            :|.|..|..|.|.|.::.:  :.|| .|.::.|||:|.||||.|||.||.....|.||:......
Mouse    29 TSPIRTTHTGQILGSLIHM--KDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHP 91

  Fly   218 PVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSS 282
            .:|   |.||   ||    |.....:.||..||... .||||||||||.|
Mouse    92 AMC---LQDI---TA----MNMQAFKLLKLTLPPFP-MSEDCLYLNIYAP--------------- 130

  Fly   283 SAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQIL 347
                                   ..|..||  ..||:|::||.|......:.||||:||:...::
Mouse   131 -----------------------DHAHEGS--NLPVMVWIHGGSLVIGMASMYDGSMLAAMENVV 170

  Fly   348 VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAAC 412
            ||||.||||||||.:...:|   ...|:|.:|.:|||.||::|||.|||:|:.:|:.|...|...
Mouse   171 VVTIQYRLGVLGFFSTGDER---ARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTS 232

  Fly   413 VHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK 477
            |..|:.| .:.:| ||..||:.||..|.. ||:|..:........:::....:....|:.|||.|
Mouse   233 VSSLVVS-PMSQG-LFRGAIMESGVALIS-SLISVSSDVVYQTVANLSGCEQVDSEALVNCLRGK 294

  Fly   478 TLDQLLSVPIRPPEFGFAFGPSI-DGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIA 541
            :.::::::     ...|...|.| ||:      ::|..|....|.|......:. .|:..:
Mouse   295 SEEEIMAI-----NKAFKIIPGIVDGI------FLPRHPQELMASADFHPVPSI-IGVNND---- 343

  Fly   542 AAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYV 606
             ..||..|..:..|                                |.:.|::......||:.
Mouse   344 -EYGWIIPSSMSMI--------------------------------DSKKGMDRQMVQAILQR-- 373

  Fly   607 RNTYTFHLNEIFATIVNEYT-DWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSY 670
            |.|......|:...::.||. |.|.|....:..:    |.:.|...|.||.|......: |...:
Mouse   374 RATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQFK----EMMKDFTFVIPALQVAQFQRS-HAPVF 433

  Fly   671 LYVFDYQTRF--GDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTR-NYTKTEISLSEVVMFYWSNF 732
            .|.|.::..|  ...|......||:::.:||.: ..||    |: ::|:.|..||..:|.||:||
Mouse   434 FYEFQHRPSFFKDSKPSHVKADHGDEILFIFRS-FWGG----TQVDFTEEEELLSRRMMKYWANF 493

  Fly   733 VRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP- 796
            .|..|||          .|...|    |..::. .::||..||:|.:....:..||.||...:|
Mouse   494 ARQRNPN----------SEGLPY----WPMFDQ-DEQYLQLDTQPAVGRALKTRRLQFWTKTLPE 543

  Fly   797 ---------DLHK 800
                     |.||
Mouse   544 KIQELKDIEDRHK 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	179/642 (28%)
		Aes	<313..>410	CDD:223730	42/96 (44%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	179/641 (28%)
		Aes	<127..>230	CDD:223730	48/145 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740