Protein Alignment Nlg3 and Nlg1

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_731172.2
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 1080
• Identity: 307/1080 - (28%)
• Similarity: 468/1080 - (43%)
• Gaps: 237/1080 - (21%)

  Fly    61 GNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNS 125
            |:::|:.:..|.....    ||..:...:..|..||.......|:...:...::....:.:..|:
  Fly    60 GDITTTIQPDSDPGRS----IGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNT 120

  Fly   126 NRSSRPTSNNSNSNSNYSPNHDQ----LPAQLS-SRIINTRNGAISGVIVQLD-GRHLDPVEAYR 184
            ..:...|...|:.:...:.:|.:    :|.:|. ::.|..:.|.:.|:..:.. ...|..|:.:.
  Fly   121 TAAVLATDEGSSEHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFL 185

  Fly   185 GIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDI--HNETAALERMPKGRLEYLKR 247
            |:|||..|.||.|||||.:...|.|:|.|....|||||:|||:  |..    |.|.:.|.::|.|
  Fly   186 GLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGS----ENMSRARHKHLSR 246

  Fly   248 LLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGS 312
            |||||:.:||||||||:|||                             .....||
  Fly   247 LLPYLRTESEDCLYLNLYVP-----------------------------HEEPQST--------- 273

  Fly   313 PAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGL 377
            |.:|.|||::||||:|||||||||||||:|||:::|||:||||||||||..:.|.::  .|||.|
  Fly   274 PKQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHN--IANYAL 336

  Fly   378 MDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPW 442
            :|.||||||:||||.|||||.:.:||.||.||||||::|:.| .|..| ||:||||||||.::.|
  Fly   337 LDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVS-PVASG-LFHRAILMSGSAMSDW 399

  Fly   443 SLVSNPAKYAAIVAHHVNCASDLPHAH------LMKCLREKTLDQLLSVPIRPPEFGFAFGPSID 501
            :..:...:....:||.:.|..: .|..      |:.|||.:....:|.:|....:|..:.||.:|
  Fly   400 AASNQSLQLTMQIAHALECPLN-EHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVD 463

  Fly   502 GVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKL 566
            |.||         |..|..                                   |:...|  ...
  Fly   464 GHVI---------PNQPYK-----------------------------------VMGHYT--EHF 482

  Fly   567 SRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTD-WER 630
            |||||:.|:|.:|::.:..:..::.|:..:.|..:|:.|:::.:....:...|..:.:|.| :..
  Fly   483 SRYDLLFGITESESYHTLAALALEEGLRENERDNLLRFYMQSRFDIRPDLALAATLKKYQDMYNN 547

  Fly   631 PVQHP-INIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGED 694
            |::.. :..||..|:.||||:||.|..||...|:..:|.:|:|||.:.:..|.:......|.||:
  Fly   548 PIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSATGPFAHLPHSIMGEE 612

  Fly   695 LPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQME----TEHGSRQERSRY 755
            |.:||||||.......:.|||..|..|||.||.||:|||:||||....:    ..|.  .|..||
  Fly   613 LAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHA--LEWDRY 675

  Fly   756 KTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPD-----------LHKPGGDNV--- 806
             .::|..:....:.|||....|.:...||...::||...:||           |.|||.:.:
  Fly   676 -DLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGH 739

  Fly   807 -----PAAH---------------------------------------------HQLHDDDDEDN 821
                 |..|                                             |::....|.::
  Fly   740 MSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFED 804

  Fly   822 NIPSDASVK-----PLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYG---- 877
            .:.|..|::     |..||  ...|.:.|.....|....:..:|||....:.|.|...|..
  Fly   805 LVTSTNSLESGEDHPQAPP--ETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALP 867

  Fly   878 ------GGKIYPDDMMDGDHAGGAASASQDSDGFAAYSTALSVTI--------AIGCSLLILNVL 928
                  ||.|...|..:.:.....:.:....|.|....|..|.|.        ::.||.:..:..
  Fly   868 FPAPKLGGTILSYDGANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTK 932

  Fly   929 IFAGVYYQR----DKTRLSEPRPQTKLKRQENGQMPNNICGDLETLTIHAKSDPATILSHH-HAM 988
            :...:..|.    .....:.|.||..|   .:|::  .||.|:|.      :|.|.::..| |..
  Fly   933 VCEWMSSQEAPKSGSFNTATPPPQPIL---SDGRL--IICQDIEV------ADAALLIPQHMHEP 986

  Fly   989 QHHQL----------PPPEFADIPHRAPPPPKHMKSLQDP 1018
            ||:::          .|.:  :|..:..|...|..|..||
  Fly   987 QHYEMLLQRQHSALTEPSD--EILQQQYPLRNHSHSHSDP 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	232/652 (36%)
Nlg1	NP_731172.2	COesterase	157..710	CDD:395084	232/648 (36%)