Protein Alignment Nlg3 and alpha-Est2

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 166/688 - (24%)
• Similarity: 259/688 - (37%)
• Gaps: 208/688 - (30%)

  Fly   157 IINTRNGAISGVIVQLDGRHL---DPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            |::|:.|.:.|    |..:.:   :|..|:.|||||.||||:|||..|.....|.||
  Fly    34 ILDTKYGQVRG----LQRKTVYDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGV-------- 86

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSS 283
                 |....|.:..::|          .:|..:...|||||:||:||
  Fly    87 -----LNCTTNRSKPMQR----------NMLLGIVEGSEDCLHLNVYV----------------- 119

  Fly   284 AGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWN--SGNPYDGSVLASYGQI 346
                                  .:..|..|  .||:|:::|..::..  |.:.|....... ..:
  Fly   120 ----------------------KALKSEKP--LPVIVWIYGGGFQKGEASRDIYSPDYFMK-KPV 159

  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411
            :.|.|||||..||||:.. |....:|.|.||.|.:.||.|:.:|||.|.||||:|||.|...|:|
  Fly   160 VFVAINYRLAALGFLSLK-DPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSA 223

  Fly   412 CVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNP-AKYAAIVAHHVNCASDLPHAHLMK--- 472
            .||.::::... .| ||::||:.||..|:.|  |.:| ..:|..:|.::....|...|.::.
  Fly   224 SVHVMMTTEQT-RG-LFHKAIMQSGCALSEW--VESPDNNWAFRLAQNLGYKGDEKDADVLSFLS 284

  Fly   473 --CLRE--------KTLDQLLSVPIRPPEFGFAFGPSIDGVVID---------------GGDYVP 512
              |.|:        ..||::.|..:      |||||.|:....|               .|:.:|
  Fly   285 KVCARQIAAIDQDVINLDEVRSFLL------FAFGPVIEPYETDHCVVPKRHKDLLSEAWGNDIP 343

  Fly   513 PAPGSPAAQAQAQASTAAGNGLGG--EAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGV 575
            ...|              ||...|  ...:.....|... ...||:.......:.|...||:  |
  Fly   344 VIVG--------------GNSFEGLFSYQLVRKDPWALK-NFHNILPREVRETSSLEGQDLL--V 391

  Fly   576 TRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRD 640
            .|.:..: ||: ::|..:|                .|....||:         .|.:.|
  Fly   392 RRLKQLY-FNN-EMQESME----------------MFEALNIFS---------HRQIWH------ 423

  Fly   641 ETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQT-RFGDY------PQRQGCIHGEDLPYI 698
            :|...:...|..||...|           |||.||:.: .|..:      .:.:|..|.::|.|:
  Fly   424 DTHRFILARQSYAPKTPT-----------YLYRFDFDSPHFNQFRRLVCGDRIRGVAHADELSYL 477

  Fly   699 FGAPLVGGFNHFTRNYTKT--EISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWT 761
            |       :|.......|:  |....|.::..|::|..:||||   ..|.||         .:|.
  Fly   478 F-------YNIIASKLDKSSMEYKTIERMVGMWTSFASSGNPN---CPELGS---------AKWE 523

  Fly   762 AY---ESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP 796
            |.   |:..:|..|.....::::...:..|:.|....|
  Fly   524 AVQLKENAVEKCFNISHDLEMRDLPESDCLAVWDTFYP 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	164/681 (24%)
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	164/681 (24%)