Protein Alignment Nlg3 and alpha-Est3

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 175/688 - (25%)
• Similarity: 261/688 - (37%)
• Gaps: 202/688 - (29%)

  Fly   153 LSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFS 217
            :.|..:||.:|.:.|  .|..|.:.|...::..||||.||||:||||.|:....||        .
  Fly     1 MESLQVNTTSGPVLG--KQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWS--------Q 55

  Fly   218 PV-C--PQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            |: |  |.:.|...|             .|.|:|     ...|||||||:|
  Fly    56 PLDCTKPGQKPLQFN-------------HYSKQL-----EGVEDCLYLNVY-------------- 88

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASY- 343
                                       :....||...|::||..|..:|  .|:|........|
  Fly    89 ---------------------------AKELDSPRPLPLIVFFFGGGFE--KGDPTKELHSPDYF 124

  Fly   344 --GQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGH 406
              ..::|||::||:|.||||:.| |....:|.|.||.|.:.|:.|:|||...|.|||.::|..|.
  Fly   125 MMRDVVVVTVSYRVGPLGFLSLN-DPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGE 188

  Fly   407 GTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSL--VSN-PAKYAAIV----AHHVNCASD 464
            ..|||.||:|:.:... || ||::|||.||:.|..|:|  :.| |.:.|..:    |.||..|..
  Fly   189 SAGAASVHYLMLNPKA-EG-LFHKAILQSGNVLCSWALCTIKNLPHRLAVNLGMESAEHVTDAMV 251

  Fly   465 LPHAHLMKCLREKTL-DQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVP------PAPGSPAAQA 522
            |.  .|.|...||.: ..|||......:..|.|||.::          |      ..|..|
  Fly   252 LD--FLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVE----------PYKTEHCALPNHP---- 300

  Fly   523 QAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG 587
            |.....|.||.:.                    |||..|:...|..|   |.|..|....:....
  Fly   301 QELLDKAWGNRIP--------------------VLMSGTSFEGLLMY---ARVQMAPYLLTSLKK 342

  Fly   588 DVQYGIEADRRSRILKAYVRNTYTFHLNE--------------IFATIVNEYTDWE--RPVQHPI 636
            :.::.:..|.:..:.:|..|     ||.:              :....:..|.::.  :...|||
  Fly   343 EPEHMLPLDVKRNLPQALAR-----HLGQRLQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPI 402

  Fly   637 NIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYP----QR--------QGC 689
                  |:.|. ::|.:.:|.|           |||.||:     |.|    ||        :|.
  Fly   403 ------LKTLR-SRVKSSSAST-----------YLYRFDF-----DSPTFNHQRLKYCGDKLRGV 444

  Fly   690 IHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSR 754
            .|.:|..|::    .|.|:.....:|...:::..::... ::|.||.|||.::..:...|.:
  Fly   445 AHVDDHSYLW----YGDFSWKLDKHTPEFLTIERMIDML-TSFARTSNPNCKLIQDQLPRAK--- 501

  Fly   755 YKTIEWTAYESVHK-KYLNFDTKPKLKNHYRAHRLSFW 791
                ||....|... :.||.....|:.......:|..|
  Fly   502 ----EWKPLNSKSALECLNISENIKMMELPELQKLRVW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	174/685 (25%)
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	174/685 (25%)