Protein Alignment Nlg3 and alpha-Est6

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 155/659 - (23%)
• Similarity: 242/659 - (36%)
• Gaps: 239/659 - (36%)

  Fly   148 QLPAQLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKK 212
            |......|:::....|::.|  .:|.|.:.|...::.|||:|.||:|..||:....|..|:....
  Fly    33 QSAGDADSKVVKLSVGSVKG--RRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELD 95

  Fly   213 ADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSG 277
            |.:..|:..|           ::|. .|::.           .||||||||:|
  Fly    96 ARQERPIPLQ-----------MDRR-SGKVV-----------GSEDCLYLNVY------------ 125

  Fly   278 SSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS 342
                                        :...:.|....||:|:::|.::...      |:|.:.
  Fly   126 ----------------------------TKHFNESEPPLPVMVYIYGGAFRTG------GAVKSK 156

  Fly   343 YG-------QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNS 400
            ||       .::.|..||||..||||:..:.:.. :|.|.||.|.:.||.|:.::|..|.|||.:
  Fly   157 YGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLD-VPGNAGLHDQLLALQWVSQHIRNFNGDPQN 220

  Fly   401 ITLAGHGTGAACVHFLISSMAVPEGL-LFNRAILMSGSGLAPWSLVSNPAK-----YAAIVAHHV 459
            |||.|...|||.|||:   |.:|:.. ||::||:||||.|:||  |:.|..     ..|..|.:.
  Fly   221 ITLFGESAGAASVHFM---MCLPQAKGLFHKAIMMSGSMLSPW--VNAPDSDGIFCRLATSAGYE 280

  Fly   460 NCASDLPHAHLMKCLREKTLDQLLSVPIRPPE---FGF--AFGPSIDGVVIDGGDYVPPAPGSPA 519
            ..|.::|   :::.||....::|:......|.   |||  .|.|.:.|:|           .:|.
  Fly   281 GPAEEVP---ILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLV-----------AAPF 331

  Fly   520 AQAQAQASTAAGNGLGGEAGIAAAGGWGTPG-------QLENIVLM------------------- 558
            .|...:|.:.       |..: ..||....|       ||:|..::
  Fly   332 QQLMKEAWSC-------EVPL-LLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSM 388

  Fly   559 ----RKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFA 619
                |.||.:.|.:|                    .||.....:|.|.:  :.:.:::.|
  Fly   389 SVEERNTAADVLVKY--------------------HYGPRGITKSNITQ--ILDLFSYKL----- 426

  Fly   620 TIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYP 684
                   .|.       .|....|..||.||  ||              :|||.||:     |.|
  Fly   427 -------FWH-------GIHRVVLSRLSHAQ--AP--------------TYLYRFDF-----DSP 456

  Fly   685 Q-------------RQGCIHGEDLPYIF------GAPLVGGFNHFTRNYTKTEISLSEVVMFYWS 730
            :             ::|..|.:||.|||      ..||           ...|....:.::...:
  Fly   457 KLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPL-----------DSPEFLTIQRMVGILT 510

  Fly   731 NFVRTGNPN 739
            .|.|||:||
  Fly   511 TFARTGDPN 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	154/656 (23%)
		Aes	<313..>410	CDD:223730	34/103 (33%)
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	154/657 (23%)
		Aes	<133..325	CDD:223730	68/206 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830