Protein Alignment Nlg3 and alpha-Est8

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_524259.2
• Gene: alpha-Est8 / 40899
• FlyBaseID: FBgn0015576
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 164/679 - (24%)
• Similarity: 247/679 - (36%)
• Gaps: 192/679 - (28%)

  Fly   157 IINTRNGAISGVIVQ-LDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD--RFSP 218
            |.:|..|.:.||..| :.|.:   ..::.|||:|.||||.|||..||....||.||:..  |..|
  Fly    34 IADTVYGKVKGVKWQSIYGNN---YYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKP 95

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYV-------PIQVGSRDSS 276
             |...:                       :|..:|. ||||||||:|.       |:
  Fly    96 -CQVNI-----------------------VLKQVQG-SEDCLYLNVYTRELHPHRPL-------- 127

  Fly   277 GSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWN--SGNPYDGSV 339
                                                    ||||:::|..::..  |.:.|....
  Fly   128 ----------------------------------------PVLVWIYGGGFQMGEASRDLYSPDY 152

  Fly   340 LASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLA 404
            :.....:||| |:||||.||||:. .|....:|.|.||.|.:.||.|:|.|...|||||::||:.
  Fly   153 IMMEHVVLVV-ISYRLGALGFLSL-ADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVF 215

  Fly   405 GHGTGAACVHF-LISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLP-- 466
            |...|.|..|: :::..|  :| ||::.|:||||.||||:.......:...:|.......|..
  Fly   216 GESAGGASTHYMMLTDQA--KG-LFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDR 277

  Fly   467 --HAHLMKCLRE---KTLDQLLSVPIRPPEFG-FAFGPSIDGVVIDGGDYVPP---APGSPAAQ- 521
              .|||.||...   |..:.::::..|..... |:|||:|:       .|:.|   .|.||...
  Fly   278 DIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIE-------PYLTPHCVIPKSPLEMM 335

  Fly   522 ----AQAQASTAAGNGLGGEAGIAAAGGWGTP------GQLENIVLMRKTAINKLSRYDLMAGVT 576
                ..:......||...|.........|  |      |..||           |:..|......
  Fly   336 RDCWGNSIPMVIGGNSFEGLLMFPEVNKW--PELLCQLGDCEN-----------LAPQDAHVDEQ 387

  Fly   577 RAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDE 641
            :.:| |.....::.:|.....|..||:.....:|.:..:.|..|:::.       ..|
  Fly   388 QRKA-FGKKVRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSR-------AHH------- 437

  Fly   642 TLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDY-------PQRQGCIHGEDLPYIF 699
                       ||.|.|           :||.||:.::..:.       .:.:|..|.:||.|:|
  Fly   438 -----------APLAPT-----------FLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLF 480

  Fly   700 GAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYE 764
            ...........|..:...:..:|.||     :|..:|:||..|..:....|.|.     .|....
  Fly   481 YNAAAKKLKRRTAEFKTIKRLVSMVV-----HFAISGDPNIPMVCQDEKEQPRG-----AWLPIS 535

  Fly   765 SVHKKY--LNFDTKPKLKNHYRAHRLSFW 791
            ...|.:  ||......:.:...|.:|..|
  Fly   536 KDDKVFQCLNISHDVHVIDLPEAEKLRLW 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	163/677 (24%)
		Aes	<313..>410	CDD:223730	38/98 (39%)
alpha-Est8	NP_524259.2	COesterase	29..564	CDD:278561	163/677 (24%)
		Aes	<116..>221	CDD:223730	40/154 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440327
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740