Protein Alignment Nlg3 and Jhedup

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_611085.2
• Gene: Jhedup / 36779
• FlyBaseID: FBgn0034076
• Length: 559
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 142/627 - (22%)
• Similarity: 229/627 - (36%)
• Gaps: 190/627 - (30%)

  Fly   163 GAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDI 227
            |.:.|.:  :.|......||:.|||:|.||||.||...||....|.||..|......|.||
  Fly    28 GCMRGTL--MPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQR---- 86

  Fly   228 HNETAALERMPKGRLEYLKRLLPYLQNQ-----SEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSS 287
                                  .|...:     .|||||||:|.|
  Fly    87 ----------------------SYFAKEWGLMGVEDCLYLNVYRP-------------------- 109

  Fly   288 SSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDG--SVLASYGQILVVT 350
                                 .:.:..|.||:|::||..:...|.:|...  ..|....::::||
  Fly   110 ---------------------KNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVT 153

  Fly   351 INYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHF 415
            :|||||..|||:...:.   :|.|:|..|...||.|::::||.|||||..:|:.||..|....|.
  Fly   154 MNYRLGPFGFLSTGDEH---MPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHL 215

  Fly   416 -LISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHH--VNCASDLPHAHLMKCLREK 477
             :||..:  :||..|...|.....|:...::.:|...|..:...  ::.|..|....|.:.||..
  Fly   216 HMISPNS--KGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNV 278

  Fly   478 TLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVP----------PAPGSPAAQAQAQASTAAG- 531
            ...:||              .|:|.:.:  .|.:|          |:|.:...:....|..|..
  Fly   279 CPKKLL--------------VSVDSLKV--WDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRI 327

  Fly   532 NGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQY----- 591
            |.:.....:::..|.|      ::.:||.....||          |||    ||...:::
  Fly   328 NQMPWILSLSSRAGEG------SLFIMRAFINPKL----------RAE----FNENFLEHMALLL 372

  Fly   592 ----GIEADRRSRILKAY------VRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEAL 646
                |......|.||.||      :.|.....|.||.... |.|        :||.   ||:.:.
  Fly   373 NLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDF-NFY--------YPIY---ETISSY 425

  Fly   647 SDAQVVAPAAQTVDLHSADHRNSYLYVFDYQ-----TRF-----GDYPQRQGCIHGEDLPYIFGA 701
                        |...:.:....::|:|::.     |:|     .||  ..|.:|.:|..:....
  Fly   426 ------------VTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDY--GLGAVHMDDGLHTIRI 476

  Fly   702 PLVGGFNHFTRNYTKTEI--SLSEVVMFYWSNFVRTGNPNEQ 741
            |:  .|:.|.::....::  .:|.::    ::|.:||..:|:
  Fly   477 PV--SFDDFPKDSEDAKVIQRMSSLM----TDFAKTGVFHEE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	142/627 (23%)
Jhedup	NP_611085.2	alpha/beta hydrolases	31..508	CDD:473884	139/618 (22%)