Protein Alignment Nlg3 and Nlg3

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 1016
• Identity: 661/1016 - (65%)
• Similarity: 759/1016 - (74%)
• Gaps: 145/1016 - (14%)

  Fly    97 TSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTR 161
            |.|..|.::|.||.|||||||:.:..|.||  ..|.||:.:.|       :.|....||||::|:
Mosquito    14 TVSLVAPINSAGSGSSSSSSSSGSGNSPSN--GGPGSNSMDEN-------ETLKKSTSSRIVHTK 69

  Fly   162 NGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPD 226
            .||:||.|..|||||||||||:||:||||||||||||||||:.|:||||||||||||||||||||
Mosquito    70 YGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKKADRFSPVCPQRLPD 134

  Fly   227 IHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGS 291
            |:||||||||||:||||||:||||||:||||||||||||||.|.|||:||.:|
Mosquito   135 IYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTS------------ 187

  Fly   292 GGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLG 356
                                   ||.|:|||||||||||||||||||||||||||||||||||||
Mosquito   188 -----------------------KYAVVVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLG 229

  Fly   357 VLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMA 421
            :|||||||.||:||.|||||||||||||||::|||.||||||.|:||||||||||||||||:|.|
Mosquito   230 ILGFLNANVDRFSKAPANYGLMDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAA 294

  Fly   422 VPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVP 486
            |||||||:|||:||||||||||||..|||:||.|:|||||:.||||..|:||||:|.|:.:||..
Mosquito   295 VPEGLLFHRAIMMSGSGLAPWSLVGEPAKFAAYVSHHVNCSPDLPHQLLLKCLRDKPLEDILSTS 359

  Fly   487 IRPPEFGFAFGPSIDGVVIDGG-----------DYV-PPAPGSPAAQAQAQASTAAGNGLGGEAG 539
            :|.|:||.|||||:||||||.|           ||. .||...|:|......:|.
Mosquito   360 VRAPDFGNAFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTI---------- 414

  Fly   540 IAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKA 604
                          |.:|:||.||||||:|||:.|||||||:|:|||.|||||||||||::|||.
Mosquito   415 --------------NAILLRKLAINKLSKYDLLVGVTRAEAYFAFNSEDVQYGIEADRRAKILKN 465

  Fly   605 YVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNS 669
            |||:||:||||||.|||||||||||||||||||||||||||||||::||||.||.||||||||||
Mosquito   466 YVRSTYSFHLNEILATIVNEYTDWERPVQHPINIRDETLEALSDARIVAPAVQTADLHSADHRNS 530

  Fly   670 YLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVR 734
            :||||||||:|||:||||||||||||||:||||||||||||||||||:||:|||.||.|||||:|
Mosquito   531 FLYVFDYQTKFGDFPQRQGCIHGEDLPYLFGAPLVGGFNHFTRNYTKSEIALSEAVMIYWSNFIR 595

  Fly   735 TGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLH 799
            |||||||:|.:|  .::|:|:|.||||.||||||||||.|||||||||||||||||||||:||||
Mosquito   596 TGNPNEQLENDH--VRDRTRFKNIEWTPYESVHKKYLNLDTKPKLKNHYRAHRLSFWLNLVPDLH 658

  Fly   800 KPGGDNVPAAHHQLHDDDDEDNNIPSD-ASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLS 863
            |||.|:||:.||:|..||:|.   |:. .:|||||||   :...|...:|:|:||.|||||||.|
Mosquito   659 KPGNDDVPSGHHELESDDEEQ---PAALPTVKPLNPP---QRDPATIGSNYTLFTTQVFSLLNFS 717

  Fly   864 S----PSSSLQRNGTRYGGGKIYP---------DDMMDGDHAGGAA------SASQDSDGFAAYS 909
            |    |:.|....|||    .::|         ||  ||..|||.|      |:||: |||||||
Mosquito   718 SYGILPNGSRHYPGTR----PVHPVTAESSEGGDD--DGGAAGGGAGGAGGMSSSQE-DGFAAYS 775

  Fly   910 TALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRP--------------QTKLKRQENGQMP 960
            |||||||||||||||||||||||||||||||||:|||.              ||| ||.||||||
Mosquito   776 TALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLNEPRGGGPGMGGPGGHGTLQTK-KRNENGQMP 839

  Fly   961 NNICGDLETLTIHAKSDPATILSHHH-AMQHHQLPPPEFADIPHRAPPPPKHMKSLQDPGGGGSV 1024
            |||||:||:||||||:||:|||.||| |:||||:|||||||:|.||||||||:||:...|||
Mosquito   840 NNICGELESLTIHAKADPSTILGHHHPALQHHQMPPPEFADLPQRAPPPPKHLKSVPGDGGG--- 901

  Fly  1025 SGAVGVSGVVQMPPPHALQVMGNQCGTLTKKSCMKQTQAQA 1065
                       |.|.||||::|:.|||||||||:|...:.|
Mosquito   902 -----------MLPAHALQLIGSNCGTLTKKSCVKSNLSAA 931

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	461/648 (71%)
Nlg3	XP_061500330.1	None