Protein Alignment Nlg3 and Ces5a

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 186/687 - (27%)
• Similarity: 266/687 - (38%)
• Gaps: 227/687 - (33%)

  Fly   160 TRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRL 224
            ||.|.:.|....:.|| |:||..:.|||:|:||:|.|||..|.....|..:::|..:..||.|
  Rat    35 TRLGWVQGKQATVLGR-LEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQ-- 96

  Fly   225 PDIHNETAALERMPKGRLEYL---KRLL----PYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSS 282
                            .||:|   :.||    |.| ..||||||||||.|
  Rat    97 ----------------NLEWLFIYQNLLKVHYPKL-GVSEDCLYLNIYAP--------------- 129

  Fly   283 SAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQIL 347
                                   :.|..||  :.||::::.|..:|..|.:.:|||.||:|..:|
  Rat   130 -----------------------AYANDGS--RLPVMMWIPGGGFETGSASIFDGSALAAYEDVL 169

  Fly   348 VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAAC 412
            :|||.||||:.||.|.....   .|.|:...|.:|||.|::|||..|||:|:|:|:.|...||..
  Rat   170 IVTIQYRLGIFGFFNTQNQH---APGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAIS 231

  Fly   413 VHFLISSMAVPEGLLFNRAILMSGSGLAPWSL--VSNPAKYA-AIVAHHVNC-ASDLPHAHLMKC 473
            :..||.| .:..| ||:|||:.||..:.| ||  ..:..|:. .:||....| .||  ...|:||
  Rat   232 ISSLILS-PLSAG-LFHRAIMQSGVAIIP-SLKNFDDELKHGLQVVADVCKCNVSD--SKVLLKC 291

  Fly   474 LREKTLDQLLSV----------------PIRPPEF----GFAFGPSIDGVVIDGGDYVPPAPGSP 518
            ||||:..:|||:                |..|.|.    .|...|||.||......|:.|...:|
  Rat   292 LREKSSLELLSLGQKTKAFTRVVDGSFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAP 356

  Fly   519 AAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFS 583
            .....:..|||.                              |.|:.|
  Rat   357 EILFGSNESTAL------------------------------TLIHVL----------------- 374

  Fly   584 FNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSD 648
                                        .|:...:..||.:  |:........:|||..|:...|
  Rat   375 ----------------------------LHIPPQYMHIVAK--DYFHGKHSLTDIRDTLLDLFGD 409

  Fly   649 AQVVAPAAQTVDLHSADHRNS----YLYVFDYQTRFGDYPQRQGCI-----------HGEDLPYI 698
            ...|.|...|    :.:||::    |.|.|.:         |..|.           |.:::.::
  Rat   410 VFFVVPGLVT----ARNHRDAGGPVYFYEFQH---------RPNCFQNTRPAFVKADHTDEIRFV 461

  Fly   699 FGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPN-EQMETEHGSRQERSRYKTIEWTA 762
            ||.|.:.|........|:.|..||..:|.||:||.|:|:|| :.:..               |.|
  Rat   462 FGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDDLPL---------------WPA 511

  Fly   763 Y---ESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP 796
            |   ||..|..:|..|..:||:    .|:.||.:.:|
  Rat   512 YDQNESYLKLDVNISTGWRLKD----RRVEFWTDTLP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	183/680 (27%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	183/680 (27%)