Protein Alignment Nlg3 and Ces2i

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_008758816.2
• Gene: Ces2i / 292152
• RGDID: 1565045
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 667
• Identity: 183/667 - (27%)
• Similarity: 280/667 - (41%)
• Gaps: 178/667 - (26%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            :|.|.||:.|.:.|..|.:.... ..|..:.|||:|.||||.|.|.||.....||||:.......
  Rat    30 ASPIRNTQTGQVRGSFVHVKDTK-SGVHTFLGIPFAKPPVGPLHFAPPEDPEPWSGVRDGTSQPD 93

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLK--RLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSS 281
            :|.|  .||..|            :::|  :|..:....||||||||||.|
  Rat    94 MCLQ--TDIMKE------------DFIKEMKLTMHPTPMSEDCLYLNIYTP-------------- 130

  Fly   282 SSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQI 346
                                    :.|..||  ..||:|::||......|.:....|.||:..:|
  Rat   131 ------------------------AHAREGS--NLPVMVWIHGGGLVLGSASMNVASTLAATEEI 169

  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411
            ::|.|.||||:|||.:.. |.:::  .|:|.:|.:|||.|:::|||.|||:...:|:.|...|..
  Rat   170 VIVAIQYRLGILGFFSTG-DEHAR--GNWGYLDQVAALCWVQQNIAYFGGNHGKVTIFGVSAGGT 231

  Fly   412 CV-HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYA-AIVAHHVNC-ASDLPHAHLMKC 473
            .| ..::|.|:  :| ||:.||:.||..|.| .|:|:.::.. ..||:...| |||  ...|::|
  Rat   232 SVSSHVVSPMS--KG-LFHGAIMQSGVALLP-DLISDTSEVVYKTVANLSGCEASD--SEALIRC 290

  Fly   474 LREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGN------ 532
            ||.|:..::|::       ...| ..|.|||  .|.::|..|         |...|:|:
  Rat   291 LRAKSKQEILAI-------NQVF-KMIPGVV--DGKFLPKHP---------QELLASGDFHPVPS 336

  Fly   533 --GLG-GEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIE 594
              |:. .|.|:......|    |::|       |.|::| |.:..|.::.|        .|..:.
  Rat   337 IIGVNTDECGLGVPMFMG----LDHI-------IKKITR-DTLPTVLKSTA--------AQMMLP 381

  Fly   595 ADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTV 659
            .:....|::.|:.:|                       :.|..::::..|.|.|...|.||
  Rat   382 PECIDLIMEEYMGDT-----------------------EDPETLQEQFKEMLGDFMFVIPA---- 419

  Fly   660 DLHSADHRNS----YLYVFDY------QTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNY 714
             |..|..:.|    |.|.|.:      |.|    |......||:|:.::|.: ...|.|.   :.
  Rat   420 -LEVAHFQRSQAPVYFYEFQHLPSFIKQVR----PSHVKADHGDDILFVFSS-YFWGMNF---DI 475

  Fly   715 TKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKL 779
            |:.|..|...||.||:||.|.||||          .|...|    |...:. :::||..:|:|.:
  Rat   476 TEEEELLKRRVMKYWANFARNGNPN----------SEDLPY----WPVLDH-NEQYLQLNTQPAV 525

  Fly   780 KNHYRAHRLSFWLNLIP 796
            ....:|.||.||...:|
  Rat   526 GRALKARRLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	180/660 (27%)
		Aes	<313..>410	CDD:223730	35/96 (36%)
Ces2i	XP_008758816.2	COesterase	30..537	CDD:395084	180/660 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840