Protein Alignment Nlg3 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 170/666 - (25%)
• Similarity: 281/666 - (42%)
• Gaps: 171/666 - (25%)

  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221
            ::.|::|.:.|..|.:..   .|:..:.|:|::.||||..||.||.....|:|::.|..:.|.|
  Rat    35 LLITKHGILQGKQVHVGD---TPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSC- 95

  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGS 286
              |.:...:..::....:.:.|:|        :.||||||||:|.|:
  Rat    96 --LQESWGQITSMYLNTRKQYEWL--------HFSEDCLYLNVYAPV------------------ 132

  Fly   287 SSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTI 351
                                 ...|.|. .||:|:..|.::...|.:.|:||.||:.|::::|.:
  Rat   133 ---------------------LAPGDPL-LPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFL 175

  Fly   352 NYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFL 416
            .||||:|||.:...   |....|:||:|.||||.|::|||.||||||:|:||.|...||..|..|
  Rat   176 QYRLGILGFFSTGN---SHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGL 237

  Fly   417 ISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQ 481
            :.| .:.:| ||::||..||:.:....:..:|.|.|..:||...|..:.... ::|||:....::
  Rat   238 LMS-PLAQG-LFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKI-MVKCLKALPAEK 299

  Fly   482 LLSVPIR-----------PPEFGFAFGPSIDG-------VVIDGGDYVPPAP---GSPAAQAQAQ 525
            ::.|..:           |.:..:...|.:||       ||:.....|.|.|   |..:|:.:
  Rat   300 VMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFE-- 362

  Fly   526 ASTAAGNGLGGEAGIAAAGGWGTPGQLE---NIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG 587
                                |..|..::   |..:|.|..|.||                 ..|.
  Rat   363 --------------------WSLPFLMKLQLNQRIMNKNYITKL-----------------LWSC 390

  Fly   588 DVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVV 652
            .:...|..::...:.:.|:.:..:.|             ||:.       .|:..::.:.||..|
  Rat   391 SILLNITEEQIPLVAREYLSDAISHH-------------DWKM-------FRNHLIDLVGDATFV 435

  Fly   653 APAAQTVDLHSADHRNSYLYVFDYQTRFGDY--PQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYT 715
            ....|....|.......|||.|.:... |..  |:..|..||::|.|:||:|    |:..:....
  Rat   436 YATLQAARYHRDAGSPVYLYEFKHHAP-GIIVKPRSDGADHGDELSYLFGSP----FSKGSSRGE 495

  Fly   716 KTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKY--LNFDTKPK 778
            :.|.||.  :|.||:||..||:||:: |..:             |..::. .:||  |:|||:..
  Rat   496 EKEFSLQ--MMKYWANFAHTGDPNDR-ELPY-------------WPRFDK-EEKYLQLDFDTRVG 543

  Fly   779 LKNHYRAHRLSFWLNL 794
            :|  .|..:::||..|
  Rat   544 VK--LREKQMTFWRRL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	167/661 (25%)
		Aes	<313..>410	CDD:223730	43/96 (45%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	167/661 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810