Protein Alignment Nlg3 and Ces2a

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_653344.1
• Gene: Ces2a / 246252
• RGDID: 708353
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 185/665 - (27%)
• Similarity: 283/665 - (42%)
• Gaps: 174/665 - (26%)

  Fly   154 SSRIINTRNGAISGVIVQL----DGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            :|.|.||..|.:.|..|.:    .|.|     .:.|||:|.||||.|||.||.....||||:.|.
  Rat    30 ASPIRNTHTGQVRGSFVHVKDTKSGIH-----TFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDAT 89

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLK--RLLPYLQNQSEDCLYLNIYVPIQVGSRDSSG 277
            ....:|.|  .||.|            |:.:|  :|..:....||||||||||.|
  Rat    90 SQPAMCLQ--TDIMN------------LDGIKEMKLTVHPTPMSEDCLYLNIYTP---------- 130

  Fly   278 SSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS 342
                                        :.|..||  ..||:|::||......|.:..|.|.||:
  Rat   131 ----------------------------AHAREGS--NLPVMVWIHGGGLVLGSASMNDASTLAA 165

  Fly   343 YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHG 407
            ..:|::|:|.||||||||.:.. |:.::  .|:|.:|.:|||.|:::|||.|||:...:|:.|..
  Rat   166 TEEIVIVSIQYRLGVLGFFSTG-DQNAR--GNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGS 227

  Fly   408 TGAACV-HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYA-AIVAHHVNCASDLPHAHL 470
            .|...| ..::|.|:  :| ||:.||:.||..|.| .|:|:.::.. ..||:...|.:....| |
  Rat   228 AGGTSVSSHVVSPMS--KG-LFHGAIMQSGVALLP-DLISDKSEVVYKTVANLSGCEAPDSEA-L 287

  Fly   471 MKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGN--- 532
            ::|||.|:..::|::       ...| ..|.|||  .|.::|..|         |...|:|:
  Rat   288 IRCLRAKSKQEILAI-------NQVF-KMIPGVV--DGKFLPKHP---------QELLASGDFHP 333

  Fly   533 -----GLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYG 592
                 |:..:     ..|||.|     :.|.....|.|::| :.:..|.::.|        .|..
  Rat   334 VPSIIGINTD-----ECGWGIP-----VFLGLDHIIKKITR-ETLPTVLKSTA--------AQMM 379

  Fly   593 IEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQ 657
            :..:....|::.|:.:|                       ::|..::::....|.|...|.||.|
  Rat   380 LPPECIDLIMEEYMGDT-----------------------ENPETLQEQFRHMLGDFMFVIPALQ 421

  Fly   658 TVDLHSADHRNSYLYVFDY------QTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTK 716
            ......: ....|.|.|.:      |.|    |......||:|:.::||:.|.|    .|.:.|:
  Rat   422 VAHFQRS-QAPVYFYEFQHLPSFIKQVR----PSHVKADHGDDILFVFGSYLWG----MTFDLTE 477

  Fly   717 TEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKN 781
            .|..|...||.||:||.||||||.: :..|             |...:. .::||..:|:|.:..
  Rat   478 EEELLKRRVMKYWANFARTGNPNGE-DLPH-------------WPVLDH-DEQYLQLNTQPAVGR 527

  Fly   782 HYRAHRLSFWLNLIP 796
            ..:|.||.||...:|
  Rat   528 ALKARRLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	182/658 (28%)
		Aes	<313..>410	CDD:223730	37/96 (39%)
Ces2a	NP_653344.1	COesterase	30..537	CDD:395084	182/658 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840