Protein Alignment Nlg3 and Ces2e

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001157228.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 668
• Identity: 181/668 - (27%)
• Similarity: 276/668 - (41%)
• Gaps: 179/668 - (26%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            :|.|.||..|.:.|.:|.:....: .|..:.|||:|.||||.|||.||.:...||||:.......
Mouse    30 ASPIRNTHTGQVRGSLVHVKDTDI-AVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSHPN 93

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSS 283
            :|      :.|:..    |....|:.:..:||.: :.||||||||||||
Mouse    94 MC------LQNDNL----MGSEDLKMMNLILPPI-SMSEDCLYLNIYVP---------------- 131

  Fly   284 AGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILV 348
                                  :.|..||  ..||:|::||.:......:.||||:||:...::|
Mouse   132 ----------------------AHAHEGS--NLPVMVWIHGGALTVGMASMYDGSMLAATEDVVV 172

  Fly   349 VTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACV 413
            |.|.||||||||.:.. |:::|  .|:|.:|.:|||.|:::||..|||:|:.:|:.|...|...|
Mouse   173 VAIQYRLGVLGFFSTG-DQHAK--GNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSV 234

  Fly   414 -HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK 477
             ..::|.|:  :| ||:.||:.||..:.|..:.|:......|||:...||: :....||.|||.|
Mouse   235 SSHVVSPMS--QG-LFHGAIMESGVAVLPDLISSSSEMVHRIVANLSGCAA-VNSETLMCCLRGK 295

  Fly   478 TLDQLLSV----------------PIRPPEF----GFAFGPSIDGVVIDGGDYVPPAPGSPAAQA 522
            ...::|::                |..|.|.    .|...|||.|:..|...::.|....||.
Mouse   296 NEAEMLAINKVFKIIPGVVDGEFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQ-- 358

  Fly   523 QAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKT--AINKLSRYDLMAGVTRAEAFFSFN 585
                                        ::|.|.  |||  |:.|.:...:|         ....
Mouse   359 ----------------------------KIEEIT--RKTLPAVLKSTALKMM---------LPPE 384

  Fly   586 SGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQ 650
            .||:           :::.|:.:|                       :.|..::.:..|...|..
Mouse   385 CGDL-----------LMEEYMGDT-----------------------EDPETLQAQFREMKGDFM 415

  Fly   651 VVAPAAQTVDLHSADHRNSYLYVFDYQ-TRFGDY-PQRQGCIHGEDLPYIFGAPLVGGFNHFTRN 713
            .|.||.|......: |...|.|.|.:: :.|.|: |......||:::..:||..    |.:....
Mouse   416 FVIPALQVAHFQRS-HAPVYFYEFQHRPSFFKDFRPPYVKADHGDEIFLVFGYQ----FGNIKLP 475

  Fly   714 YTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPK 778
            ||:.|..||..:|.||:||.|.||||          .|...|    |...:. .::||..|.:|.
Mouse   476 YTEEEEQLSRRIMKYWANFARHGNPN----------SEGLPY----WPVMDH-DEQYLQLDIQPS 525

  Fly   779 LKNHYRAHRLSFWLNLIP 796
            :....:|.||.||...:|
Mouse   526 VGRALKARRLQFWTKTLP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	178/661 (27%)
		Aes	<313..>410	CDD:223730	39/96 (41%)
Ces2e	NP_001157228.1	COesterase	30..538	CDD:278561	178/661 (27%)
		Aes	<128..>231	CDD:223730	46/145 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740