Protein Alignment Nlg3 and Ces2c

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_663578.1
• Gene: Ces2c / 234671
• MGIID: 2385905
• Length: 561
• Species: Mus musculus
• Alignment Length: 643
• Identity: 174/643 - (27%)
• Similarity: 272/643 - (42%)
• Gaps: 135/643 - (20%)

  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221
            |.||..|.|.|.::.:...... |..:.|||:|.||||.|||.||.:...||||:.......:|.
Mouse    35 IRNTHTGQIQGSLIHVKDTKAG-VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCL 98

  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGS 286
            |.| |:.||..         |..:|.:|.... .||||||||||.|
Mouse    99 QNL-DMLNEAG---------LPDMKMMLSSFP-MSEDCLYLNIYTP------------------- 133

  Fly   287 SSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTI 351
                               :.|..||  ..||:|::||.:......:.:|||:|.....::||||
Mouse   134 -------------------AHAHEGS--NLPVMVWIHGGALVIGMASMFDGSLLTVNEDLVVVTI 177

  Fly   352 NYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACV-HF 415
            .||||||||.:.. |::::  .|:|.:|..|||.|:::|||.|||:|:.:|:.|...|...| ..
Mouse   178 QYRLGVLGFFSTG-DQHAR--GNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSH 239

  Fly   416 LISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLD 480
            ::|.|:  :| ||:.||:.||..|.| .|:|..::..:.....::....:....|::|||.|:..
Mouse   240 VVSPMS--QG-LFHGAIMESGVALLP-DLISETSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEA 300

  Fly   481 QLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGG 545
            ::|::     ...|...|:    |:| |::.|..|....|........:. .|:..:     ..|
Mouse   301 EILAI-----NKVFKMIPA----VVD-GEFFPRHPKELLASEDFHPVPSI-IGVNND-----EFG 349

  Fly   546 WGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTY 610
            |..|      |:|...        .::.|:||...........||..:..:....:::.|:.:|
Mouse   350 WSIP------VVMGSA--------QMIKGITRENLQAVLKDTAVQMMLPPECSDLLMEEYMGDT- 399

  Fly   611 TFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFD 675
                 |...|:..::|                 |.:.|...|.||.|......: |...|.|.|.
Mouse   400 -----EDAQTLQIQFT-----------------EMMGDFMFVIPALQVAHFQRS-HAPVYFYEFQ 441

  Fly   676 Y-QTRFGDY-PQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNP 738
            : .:.|.|. |......|.:::|::|.:...|    ...::|:.|..||..:|.||:||.|.|||
Mouse   442 HPPSYFKDVRPPHVKADHADEIPFVFASFFWG----MKLDFTEEEELLSRRMMKYWANFARHGNP 502

  Fly   739 NEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP 796
            |          .|...|    |...:. .::||..|.:|.:....:|.||.||...:|
Mouse   503 N----------SEGLPY----WPVMDH-DEQYLQLDIQPAVGRALKAGRLQFWTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	171/636 (27%)
		Aes	<313..>410	CDD:223730	38/96 (40%)
Ces2c	NP_663578.1	COesterase	31..540	CDD:278561	171/636 (27%)
		Aes	<130..>233	CDD:223730	44/145 (30%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740