Protein Alignment Nlg3 and Ces2b

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 661
• Identity: 178/661 - (26%)
• Similarity: 270/661 - (40%)
• Gaps: 180/661 - (27%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            :|.|.||..|.:.|.:|.:...... |..:.|||:|.||||.|||.||.:...||||:.......
Mouse    32 ASPIRNTHTGQVRGSLVHVKDTKAG-VHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPA 95

  Fly   219 VCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSS 283
            :|.|.|               |.::.:|..||.: :.||||||||||.|
Mouse    96 MCLQNL---------------GVMKEIKLKLPPV-STSEDCLYLNIYTP---------------- 128

  Fly   284 AGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILV 348
                                  :.|..||  ..||:|::||........:.||||:||:...::|
Mouse   129 ----------------------AHAHEGS--NLPVMVWIHGGGLVAGMASMYDGSLLAAIEDLVV 169

  Fly   349 VTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACV 413
            |||.||||||||.:.. |::::  .|:|.:|.:|||.|:::|||.|||.|:.:|:.|...|...|
Mouse   170 VTIQYRLGVLGFFSTG-DQHAR--GNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSV 231

  Fly   414 -HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK 477
             ..::|.|:  :| ||:.||:.||..|.|:.:.......:..||....|.: :....|::|||.|
Mouse   232 SSHVVSPMS--KG-LFHGAIMESGVALLPYLITDTSEMVSTTVAKLSGCEA-MDSEALVRCLRGK 292

  Fly   478 TLDQLLSV----------------PIRPPEF----GFAFGPSIDGVVIDGGDYVPPAPGSPAAQA 522
            :..::|::                |..|.|.    .|...|||.||..|
Mouse   293 SEAEILAINKLVQMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNND---------------- 341

  Fly   523 QAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG 587
                                ..||..|     :|:.....|.:::|.:|.|.:....|
Mouse   342 --------------------EFGWTIP-----VVMGSAQTIKEITRENLQAVLKNTTA------- 374

  Fly   588 DVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVV 652
              |..:..:....:::.|:.:|      |...|:..::|                 |.:.|...|
Mouse   375 --QLMLPPECSDLLMEEYMGDT------EDAQTLQIQFT-----------------EMMEDFMFV 414

  Fly   653 APAAQTVDLHSADHRNSYLYVFDYQ-TRFGDY-PQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYT 715
            .||.| |......|.:.|.|.|.:| ....|. |......|.:::|::||.    .|.....::|
Mouse   415 IPALQ-VAYFQRSHASVYFYEFQHQIASLKDVRPTHVKADHADEIPFVFGY----FFWDMKLDFT 474

  Fly   716 KTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLK 780
            :.|..||..:|.||:||.|.||||          .|...|    |...:. .::||..||:|.:.
Mouse   475 EGEKLLSRRMMKYWANFARHGNPN----------SEGLPY----WPVMDH-DEQYLQLDTQPAVG 524

  Fly   781 NHYRAHRLSFW 791
            ...::.||.||
Mouse   525 RALKSRRLQFW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	176/659 (27%)
		Aes	<313..>410	CDD:223730	40/96 (42%)
Ces2b	NP_937814.1	COesterase	34..535	CDD:365897	175/657 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740