Protein Alignment Nlg3 and cest-31

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 166/663 - (25%)
• Similarity: 264/663 - (39%)
• Gaps: 185/663 - (27%)

  Fly   157 IINTRNGAISGVIVQLDGRH-LDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVC 220
            ::|:..|.:.|.:.    || .:.|..|.|||||.||:|.|||..||||.:|:..:...::.|.|
 Worm    16 VLNSTCGPVQGNLY----RHGNEEVHGYLGIPYAQPPIGILRFKKPVSADVWTETRDCTKYGPRC 76

  Fly   221 PQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSE-DCLYLNIYVPIQVGSRDSSGSSSSSSA 284
            |                |.|.| |....||......| :||.||::.| |...:.|
 Worm    77 P----------------PSGML-YENLQLPNTDIPDEANCLSLNVFCP-QWEIKQS--------- 114

  Fly   285 GSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPY-DGSVLAS--YGQI 346
                                         ||:||::|:||..:|.::...| |.|:..:  ...:
 Worm   115 -----------------------------AKHPVMIFIHGGGFELSASKDYCDYSLSGTLPLKDV 150

  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411
            :|||:|||:|.||||....|   ....|:||.|:..||.|:..:|::|||||.::||.|...||.
 Worm   151 IVVTVNYRVGALGFLTTGDD---SCRGNFGLWDLTLALKWVSTHISSFGGDPKNVTLFGQSAGAV 212

  Fly   412 CVHFLISSMAVPEGLLFNRAILMSGSGLAPWSL--VSNPA----KYA-------AIVAHHVNCAS 463
            |...|  :::.....||::.|:||||...|:::  ..|.|    :||       :..|..:....
 Worm   213 CADLL--NLSPYSRDLFHKLIIMSGSAHVPFAIRTEENQALVCMEYARSRGFSGSGSAELLEFFE 275

  Fly   464 DLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQAST 528
            :||   :.|.|.:..|...:|:.:       :|.|::|      ||:.|.
 Worm   276 NLP---IEKLLEKTGLKHTVSIDL-------SFAPNLD------GDFFPK--------------- 309

  Fly   529 AAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFF-SFNSGDVQYG 592
                                  .||.  |.|:|     .:..::.|:...|... :|..||.. .
 Worm   310 ----------------------PLEE--LRRET-----RKKPVIVGMMEDEGLITAFADGDFT-T 344

  Fly   593 IEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDW-----ERPVQHPINIRDETLEALSDAQVV 652
            .|.:.:.|:...| |.....:...:...|:|.||::     ||.:...|.........|..|:.:
 Worm   345 CEENFKRRVESEY-RGDVVENPENVQKNIMNFYTNYCDESEERKLVDYIGHSVYNAGVLLSAESL 408

  Fly   653 APAAQTVDLHSADHRNSYLYVFDYQTRFGDYP-----QRQGCIHGEDLPYIFGAPLVGGFNHFTR 712
            |.|...|          |.||||:....|..|     ..:|..|..:|.||.|.   |.::.|..
 Worm   409 ARAGNCV----------YFYVFDFWNPDGFGPVGSIVPFKGAAHCSELRYIIGE---GVYSKFDA 460

  Fly   713 NYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKP 777
            |  :.::.:.|.:...::||.:.||||....|...:..|.||:..|:              .|..
 Worm   461 N--EKDLKMMEYMTTMFTNFAKYGNPNIPGVTNWETYTEGSRHFHID--------------STDS 509

  Fly   778 KLKNHYRAHRLSF 790
            ::|:.::.:|..|
 Worm   510 EMKDSFQENRCQF 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	166/663 (25%)
		Aes	<313..>410	CDD:223730	39/99 (39%)
cest-31	NP_504692.3	COesterase	16..522	CDD:278561	165/661 (25%)
		Aes	<112..>211	CDD:223730	40/139 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810