Protein Alignment Nlg3 and cest-13

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 674
• Identity: 160/674 - (23%)
• Similarity: 246/674 - (36%)
• Gaps: 193/674 - (28%)

  Fly   158 INTRNGA--ISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRF-----MPPVSAAMWSGVKKADR 215
            :.|.||:  |.|:      :|.... ::|||.||.||||..||     :.||      |:.:|..
 Worm    27 VQTPNGSATIRGI------QHTYGT-SFRGIRYAQPPVGLFRFGAARRLDPV------GLVEAQA 78

  Fly   216 FSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSS 280
            :..:|.|               ..||..:            ||||::|:|.|..|
 Worm    79 YGNICVQ---------------GDGRTSH------------EDCLFINVYTPNNV---------- 106

  Fly   281 SSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSV--LASY 343
                                  |.:|        |.||.|::||..:....||...|..  |.:.
 Worm   107 ----------------------TQAS--------KLPVYVYIHGGGFVEGGGNMGAGIYPNLVNK 141

  Fly   344 GQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGT 408
            |.|::|:||||||..||.:.   |....|.|:.:.|.|.||:|::..|:.||||||.:|:.|..:
 Worm   142 GPIVMVSINYRLGPFGFFST---RQMTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQSS 203

  Fly   409 GAACVHFLISSMAVPEGLLFNRAILMSGS--GLAPWSLVSNPAKYAAIVAHHVNCASD------L 465
            ||..|..|..:.....  ||.::|..|||  |.|..|........:..::..:.||:.      .
 Worm   204 GAEAVSTLTLTPLAKN--LFKQSIHESGSAFGAAVMSYSEKTRSTSKQLSIKLGCATSDQWDNGQ 266

  Fly   466 PHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAA 530
            ....::.|||..|.|::::.....|      |..:...::....|:.......|.|...:.:...
 Worm   267 SFGTILTCLRNVTYDKIVAADNSLP------GHRMKWSIVQDNKYLTQRLEYLALQRDPKKNVLI 325

  Fly   531 GN----GLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQY 591
            |:    .|          ||.....|.||.....||  ...|.||              ||..:.
 Worm   326 GDVHDEWL----------GWEMNNVLHNINSSHNTA--HQMRDDL--------------SGSYEM 364

  Fly   592 GIEADRRSRILKA---YVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVA 653
            ....:::|.::.|   |:.|.         ....:.:.:||.          ..::..|:...:.
 Worm   365 TYWDNKQSVLVAADNKYINNQ---------GWTDDNHREWEA----------RRIQLWSEMVFIG 410

  Fly   654 PAAQTVDLHSADHRNSYLYVFDYQT----RFGDYPQRQGCIHGEDLPYIFGAPLVGGF-----NH 709
            |..:..........|.|||..|:.:    .....|..:||.|..:|.|||... ..||     :.
 Worm   411 PTLRDAAYFQYMKNNVYLYSLDWLSPPALPLVTDPLFRGCEHTWELQYIFSTS-CNGFTCTAQDE 474

  Fly   710 FTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFD 774
            ..|||..|.          |.||:..|||     |..||.      ...:|.|.:|.: ::|:|.
 Worm   475 ILRNYFTTT----------WLNFIIGGNP-----TPAGSP------LPFKWLAMDSTN-RFLSFS 517

  Fly   775 TKPKLKNHYRAHRLSFWLNLIPDL 798
            ..||::.||....: ||:...|.:
 Worm   518 PNPKMQPHYHPDSM-FWVCTAPTI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	157/665 (24%)
		Aes	<313..>410	CDD:223730	38/98 (39%)
cest-13	NP_741921.1	Abhydrolase	22..510	CDD:304388	150/640 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910