Protein Alignment Nlg3 and glit-1

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 742
• Identity: 186/742 - (25%)
• Similarity: 276/742 - (37%)
• Gaps: 236/742 - (31%)

  Fly   141 NYSPNHDQLPAQLSSRIINTRNGAISGVIVQL-----------------DGRHLDP--------- 179
            |...|.|::       ::....|.|.|..|.|                 ||.|.||
 Worm    47 NQGLNRDEV-------VVRLPLGDIVGKEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNI 104

  Fly   180 -VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKK--ADRFSPVCPQRLPDIHNETAALERMPKGR 241
             |..:.|:|||.||....||.||....::.|.:.  |..::..|.|   |:       |:.|...
 Worm   105 TVFTFLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQ---DV-------EKSPSPF 159

  Fly   242 LEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSS 306
            :::     ||.....||||||||:.|                            ..|.::.|:
 Worm   160 VDH-----PYPFMVDEDCLYLNIFSP----------------------------DISKNAQTT-- 189

  Fly   307 SAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKL 371
                     |||:||.||.:::..|.|.:....|||.|.: |||:|||||..||::.....
 Worm   190 ---------YPVIVFFHGGNFQTGSANEWPAHGLASRGMV-VVTVNYRLGAFGFMSMGDSE---- 240

  Fly   372 PANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGL-LFNRAILMS 435
            ..||||.|...||.::|.||..|||||.::|:.||..|||.:.|.:.|   |... ||..|..||
 Worm   241 TGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQS---PYSRHLFRSAATMS 302

  Fly   436 GSGLAPWSLVSNPA----------KYA----AIVAHHVNCASDLPHAHLMKCLREKT---LDQLL 483
            |:.::..|.:...|          :||    |:..|..:|           .|...|   :|...
 Worm   303 GAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDC-----------ILTRSTGDIIDATR 356

  Fly   484 SVPIRPPEFG-FAFGPSIDGVVIDGGDYVPPAP-----GSPAAQAQAQASTAAGNGLGGEAGIAA 542
            ::||   |:. :.|.|::|      |.|:|..|     .:|:.:....:......|:..:.|
 Worm   357 NIPI---EYNRYLFMPTVD------GKYLPGNPLWTLVNAPSGETSIMSPVPMLIGMNAQDG--- 409

  Fly   543 AGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAY-- 605
                      ..:||..:                |...|..||..|.:|          ||:|
 Worm   410 ----------SEVVLEDR----------------RLGEFSQFNDVDHEY----------LKSYSL 438

  Fly   606 ---VRNTYTFHLNEIFATIVNEYTDW-ERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADH 666
               .|:.|:.:.......|:::||.| :|.....  |::..::..:||...||...:..|||:..
 Worm   439 EYCYRHNYSMNREATADAILSKYTFWPDRAAAWA--IKENFIQFATDAYYTAPMQLSSHLHSSSG 501

  Fly   667 RNSYLYVFDYQTRFGD-------YPQRQGCIHGEDLPYIFGAPLVG------GFNHFTRNYTKTE 718
            ...:.||.:|  .|..       .|...|.....||..:||.|.:.      |....  |:|.|:
 Worm   502 SRVFQYVNNY--NFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFLPDELRPIGLRGI--NFTDTD 562

  Fly   719 ISLSEVVMFYWSNFVRT----GNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPK- 778
            .:.|..    :||.:|.    .|||.|.:   ||           |.|||.....|:||:...:
 Worm   563 RNASRT----FSNIIRRFSYHQNPNFQFD---GS-----------WAAYEPRRHWYINFNYTHEE 609

  Fly   779 -------LKNHYRAHRLSFWLNLIPDL 798
                   |...||...::||...||.|
 Worm   610 DWKIPGTLARDYRYQDVAFWNEYIPAL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	178/723 (25%)
		Aes	<313..>410	CDD:223730	41/96 (43%)
glit-1	NP_508807.1	COesterase	56..629	CDD:365897	178/717 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880