Protein Alignment Nlg3 and cest-26

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 739
• Identity: 180/739 - (24%)
• Similarity: 279/739 - (37%)
• Gaps: 237/739 - (32%)

  Fly   125 SNRSSRPT-------------------SNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIV 170
            |...||||                   |...::.||.:|          |:.:.||||.:.|..:
 Worm     2 SQSQSRPTPKSRTRQLWKKMGGVISFISLRHHNESNLTP----------SKQVRTRNGLVEGFRI 56

  Fly   171 QLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALE 235
            ::|...  .|:.:.|||:|..|||:|||..|.....|.||||..||.|..||  .|..     .|
 Worm    57 KIDDDR--EVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQ--ADFF-----WE 112

  Fly   236 RMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSS 300
            |...|            ..:||||||||::.|.......|:|
 Worm   113 RFTLG------------VGKSEDCLYLNVFSPTWKAEEVSNG----------------------- 142

  Fly   301 SSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASY---GQILVVTINYRLGVLGFLN 362
                          .:||:|:|||..:..:|...|....:|.|   ..::||||.||||:|||.:
 Worm   143 --------------LHPVMVYVHGGGFLIDSAVKYGDEGIAKYLCRHGVVVVTIQYRLGLLGFFS 193

  Fly   363 ANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLL 427
            ...   ...|.|.||.|:..||.|:::|:.||||||..:|:.|...|...|..|  |::.....|
 Worm   194 TGD---QVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSAGGVSVDLL--SLSPHSRDL 253

  Fly   428 FNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK-TLDQLLSVPI---- 487
            |::.:.|:|:|...||.|..        ...||...:..:   .||..|| ..|:..|..:
 Worm   254 FHQVVPMAGNGECEWSTVGK--------NRLVNACREFAY---RKCWDEKQARDENASESMLEFL 307

  Fly   488 ---RPPEFGFAF----GPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGG 545
               :..||....    |..:..:.:|    :.|..||..:..
 Worm   308 RTRKEREFEKRLLTRKGVDVSKIGLD----LAPVIGSKPSDF----------------------- 345

  Fly   546 WGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTY 610
              .|..:|.   :||.|..|    ::|.|....|.....:.|...:    |.:.
 Worm   346 --LPKSIEE---LRKEAPKK----NIMVGTCEHEGLLFASLGPSNF----DEKG----------- 386

  Fly   611 TFHLNEIFATIVNE--YTDWERPVQHPINIRDET----LEALSDAQ---VVAPAAQTVDLHSADH 666
               ::::.|.::.|  :.|:|.       :|:|.    |:.|||.:   .|| |...:.|:|...
 Worm   387 ---IDKLLALLITEENHEDFEA-------LREEAKKMYLKKLSDDEDDKEVA-ARGYIQLYSDLF 440

  Fly   667 RNS----------------YLYVFDY--QTRFGDYPQR---QGCIHGEDLPYIFGAPLVGGFNHF 710
            .|:                ::|.|||  ...||....|   :...|..:|.||||..:|  ||:
 Worm   441 VNNGTYNYAEKMTKLGNKVFMYSFDYCNPRSFGILSLRAPFRAATHCTELAYIFGVSIV--FNY- 502

  Fly   711 TRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMET--------EHGSRQERSRYKTIEWTAYESVH 767
              .|.:::.::.:::...|:||.:.||||.|.|.        |..|::|.:.:..|.
 Worm   503 --RYNESDRAMLDLMTKMWTNFAKYGNPNGQYEDSTVFDFKWEPTSKEEPTNFLAIN-------- 557

  Fly   768 KKYLNFDTKPKLKNHYRAHRLSFW 791
                  :.|.:::..|:.:|..||
 Worm   558 ------EKKCEMQTVYQDNRAEFW 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	169/692 (24%)
		Aes	<313..>410	CDD:223730	38/99 (38%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	170/699 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810