Protein Alignment Nlg3 and cest-1.1

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 677
• Identity: 150/677 - (22%)
• Similarity: 255/677 - (37%)
• Gaps: 202/677 - (29%)

  Fly   152 QLSSRIINTRNGAISGVIVQLDGRHLDPVEA--YRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            ||||       |.|.|.|:.:....|....|  :.|||:..||:|:||:..|.....|.||...:
 Worm    20 QLSS-------GTIEGKILNISYSPLGNQSATVFLGIPFVEPPIGDLRYRKPRPPKSWEGVLVTN 77

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            .:...|      :.|.|...:....|.:             ||||||||:.
 Worm    78 EYKSAC------MSNATKTYKNKFGGPI-------------SEDCLYLNVL-------------- 109

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS-- 342
                            ::.......:.|          |::.|||..|...|.:.::..:|.:
 Worm   110 ----------------TNEYCLENKNCS----------VMMIVHGGGYLTESASTFNPEILINNF 148

  Fly   343 YGQ---ILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLA 404
            .||   |:|||.|||||:..|...|.||..|   |:||.|:|.:::|::..|..|||:.|.||||
 Worm   149 VGQGRNIVVVTFNYRLGLFSFGQFNGDRGDK---NFGLYDMIESVNWVRREIENFGGNKNRITLA 210

  Fly   405 GHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKY--AAIVAHHVNCASD--- 464
            ||..||:.: ...:|..:.:||: ::.|:||    ||.:.:|..:.:  ..::|..|.|.|:
 Worm   211 GHSAGASMI-VAFTSSPLTKGLV-HQQIIMS----APMTNMSKKSNFKGMTVMAQMVGCLSEEIG 269

  Fly   465 ---LPHAHL---MKCLREKTLDQLLSVP--IRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQ 521
               |....:   ..|||:|:..|:|...  :......|...|.||...:.  ||.
 Worm   270 FNKLSEEQVENTYSCLRKKSAQQILDAQLWLLQNSTYFLGAPPIDEHFLT--DYP---------- 322

  Fly   522 AQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNS 586
                                           ||:.     |...:...:.:.|.|..|.
 Worm   323 -------------------------------ENLY-----ASKSIYPINTLIGTTTLEV------ 345

  Fly   587 GDVQYGIE---ADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSD 648
            .:..|.|:   ||::..:|:     ....|:..:   :..|...:.:..|......:.::...::
 Worm   346 EESSYIIDPAFADKKVELLE-----NLCDHIGYV---LYEEPETFSKKCQKQYMNGNSSMNLSNE 402

  Fly   649 AQVVAPAAQTVDLHSADHRNSYLYVFDYQ---TRFGDYPQRQGCIHGEDLPYIFG------APLV 704
            .:...||....|.|::.:...:||.:||:   ..:..|.:.:...|.|||.|:||      ||
 Worm   403 MEFYTPAIDFADSHTSGNTKVFLYSYDYRGAGPAYDRYLEVRSPHHSEDLIYVFGTHRGIFAP-- 465

  Fly   705 GGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKK 769
                   ::|.     :.::....:::||...||     ...|.:         :|..|...:::
 Worm   466 -------KDYI-----IEKIYSGMFADFVNFENP-----LPSGDQ---------KWNQYTKENRE 504

  Fly   770 Y--LNFDTK---PKLKNHYRAHRLSFW 791
            :  :|||..   |.::::|......||
 Worm   505 HFLINFDKNFITPGMRDNYYTEAYEFW 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	148/675 (22%)
		Aes	<313..>410	CDD:223730	40/101 (40%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	148/675 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810