Protein Alignment Nlg3 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 167/681 - (24%)
• Similarity: 260/681 - (38%)
• Gaps: 208/681 - (30%)

  Fly   158 INTRNGAISGVIVQLDGRHLDPVE---------AYRGIPYASPPVGNLRFMPPVSAAMWSGVKKA 213
            |:|:....:|:|   :|:.|:...         |:.||||..||:|:|||..|.....||||.:.
 Worm    17 ISTKVQLSTGII---EGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSGVLET 78

  Fly   214 DRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGS 278
            .:|.|.|      :.|.|...:....|.        |.    ||||||||:.
 Worm    79 KKFKPAC------MSNSTKTYKNGGIGG--------PI----SEDCLYLNVL------------- 112

  Fly   279 SSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS- 342
                             ::.......:.|          |::.|||..|.:.|...::..:|.:
 Worm   113 -----------------TNQYCLENKNCS----------VVIIVHGGGYLFESAATFNHEILVNN 150

  Fly   343 -YGQ---ILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITL 403
             .||   |:|||||||||:.||.:.|.....|   |.|:.|.:.|:.|::..|..|||:.:.|||
 Worm   151 FVGQDRNIVVVTINYRLGIFGFGHLNGFEGDK---NVGIFDTLEAVKWVRREIKQFGGNKDRITL 212

  Fly   404 AGHGTGAACV-HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAI--VAHHVNCAS-- 463
            |||..||..| .|.||.:.  :||: ::.|:|||    |.:.:|..:.:..:  :|..|.|.|
 Worm   213 AGHSAGAGVVAAFTISPLT--KGLI-HQQIVMSG----PMTNMSKKSNFKGMTAMAERVGCHSKK 270

  Fly   464 ----DLPH---AHLMKCLREKTLDQLLSVPI-RPPEFGFAFG-PSIDGVVIDGGDYVPPAPGSPA 519
                .||.   ..:..|||:|...:||...: ......|.|| |.:|      |:::...|.:
 Worm   271 YGFNKLPEHEVEQVYSCLRKKPAQELLDAQLWLLQNSTFYFGAPPVD------GEFITDYPDN-- 327

  Fly   520 AQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSF 584
              ..::.|..:.|.|.|.          |..:|::...:..:..:|..         ..|.|..
 Worm   328 --LYSEKSIFSINTLLGT----------TTRELQDTGYISNSNYSKFE---------TKETFLK- 370

  Fly   585 NSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALS-D 648
            |..| |.|||..:.|....:..:..|                         ||..|.  ::|| |
 Worm   371 NLCD-QIGIEIYKESEDFSSKCQKWY-------------------------INGSDS--KSLSDD 407

  Fly   649 AQVVAPAAQTVDLHSADHRNSYLYVFDYQ---TRFGDYPQRQGCIHGEDLPYIFG------APLV 704
            .:....|....|.|:...:..|:|.:.|.   ..|..|.:.:...|.|||.|.||      ||
 Worm   408 MEFYTQAINLADAHARKGKKVYMYSYAYSGAGPAFKKYMKVKSPHHSEDLIYTFGTHRGVFAP-- 470

  Fly   705 GGFNHFTRNYTKTEISLSEVVMFYWS----NFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYES 765
                   ::|         |:.:.:|    :|:...:|:...:.              .|..|..
 Worm   471 -------KDY---------VIEYIYSGMFADFINFEDPSPSTDQ--------------PWLQYTK 505

  Fly   766 VHKKY--LNFD---TKPKLKNHYRAHRLSFW 791
            .:|:|  ::||   |.|.:|.:|.|....||
 Worm   506 ENKEYFLVDFDQNLTMPGMKKNYYAKAYEFW 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	165/679 (24%)
		Aes	<313..>410	CDD:223730	38/101 (38%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	163/675 (24%)
		Aes	<125..>250	CDD:223730	51/134 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810