Protein Alignment Nlg3 and cest-34

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 669
• Identity: 163/669 - (24%)
• Similarity: 264/669 - (39%)
• Gaps: 195/669 - (29%)

  Fly   157 IINTRNGAISGVIVQLDGRHLD-PVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVC 220
            ::||..|.:.|.:.    ||.| .|..|.|:|||.||.|.:||..||.|..|:..:...::.|.|
 Worm    16 VLNTSCGPVLGNLY----RHGDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPRC 76

  Fly   221 PQRLPDIHNETAALERMPKGR-LEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSA 284
            |                |.|: ||....:.|...:::.. |.:|::||
 Worm    77 P----------------PSGQGLEKGMFVNPDEPDEANG-LSVNVFVP----------------- 107

  Fly   285 GSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPY-DGSVLAS--YGQI 346
                   |..||...::.              ||:|:|||..:|.:|...: |.|:.::  ...:
 Worm   108 -------GWESSEYKNAR--------------PVMVYVHGGGFEISSSREFCDYSISSTLPMKDV 151

  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411
            ::||:|||||:|||.....:   ..|.|:||.|...||.|::::||:||||||::||.|...|.|
 Worm   152 ILVTMNYRLGILGFFTTGDE---VCPGNFGLWDQTLALQWVQKHIASFGGDPNNVTLFGQSAGGA 213

  Fly   412 CVHFLISSMAVPEGL-LFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCL- 474
            ||..|..|   |... ||.:.:.||||.:         .::|...|.:        .||:...:
 Worm   214 CVDLLTLS---PHSRDLFQKVVPMSGSAM---------CEFAMRTAEN--------EAHVFDDIL 258

  Fly   475 ---------REKTLDQLLSVPIRP---------PEFGF-AFGPSIDGVVIDGGDYVPPAPGSPAA 520
                     .::.|:.:.|:|...         .:.|| :..|:.|      ||:.|    .|..
 Worm   259 ARLGFTGSGSKERLEFMRSLPCDKITGKTGYTYKQSGFMSLCPNYD------GDFFP----KPLD 313

  Fly   521 QAQAQAS-TAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGV--TRAEAFF 582
            :.:..|| .....|:.|..|:..|....||  .::...:.:..|.:..:.|::..|  .|.| .|
 Worm   314 ELRKDASKRILMTGIVGNEGLLFAFDRNTP--YKDYTDLLRLKIEEDYKEDVVDDVEGIRKE-IF 375

  Fly   583 SFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALS 647
            .:.:.::..|.|        :|.:|....|..:.||.|.|.                       :
 Worm   376 EYYTKNISEGDE--------EAIMRKAAEFVGDSIFHTGVR-----------------------A 409

  Fly   648 DAQVVAPAAQTVDLHSADHRNS-YLYVFDYQTRFGDYPQRQGCI------HGEDLPYIFGAPLVG 705
            .||           ::|:|.:. :||.|||....|..|.: |.:      ||.:|.|:||..::.
 Worm   410 TAQ-----------NAAEHGDEVWLYNFDYCNPDGFAPLK-GYLPYIEPTHGMELRYLFGDGIIS 462

  Fly   706 GFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPN-------EQMETEHGSRQERSRYKTI----- 758
            .|..     |:.|:.:.:.....::||.:.||||       |:.:.....|..|..|...
 Worm   463 KFEP-----TEEELKMLDKFTTMFANFAKYGNPNETGSSAWEKFDPARPGRHYRISYPNSGMEDE 522

  Fly   759 ----EWTAYESVHKKYLNF 773
                .|...|.:.||..:|
 Worm   523 FSGGRWKFLEEIRKKNKSF 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	163/669 (24%)
		Aes	<313..>410	CDD:223730	39/99 (39%)
cest-34	NP_001360105.1	COesterase	15..530	CDD:365897	159/656 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810