Protein Alignment Nlg3 and cest-33

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 168/676 - (24%)
• Similarity: 258/676 - (38%)
• Gaps: 192/676 - (28%)

  Fly   163 GAISGVIVQLDGRHLDP-VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPD 226
            |.:.|.|.    :|.|. |:.|.|||||.||||.|||..||:..:|:.:|...::.|.|.|
 Worm    22 GPVRGNIY----KHDDVIVDGYLGIPYAKPPVGELRFKKPVTVDVWTEIKDCYKYGPACVQ---- 78

  Fly   227 IHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGS 291
                |...|::...|..         ..:...||.||::.|....|...:|.
 Worm    79 ----TGGFEQIAGPRTP---------TPEEAGCLTLNVFTPRNASSEFKNGR------------- 117

  Fly   292 GGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGN---PYDGSVLASYGQILVVTINY 353
                                     ||:|::||..||..:.:   .|..|.......::||:|||
 Worm   118 -------------------------PVMVYIHGGGYELCASSDFCAYSLSGTLPLKDVVVVSINY 157

  Fly   354 RLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLIS 418
            ||||.|||   |...:..|.|:||.|...||.|::::|::||||||.:|:.|...|.|....|
 Worm   158 RLGVFGFL---TTGDNVCPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSAGGASTDLL-- 217

  Fly   419 SMAVPEGLLFNRAILMSGSGLAPWSL--VSNPAK-YAAIVAHHVNCASDLPHAHLMKCLREKTLD 480
            |::.....||.|.|.:||:....:::  ..|.|| :......|.....|  .:.|.|..:|::.:
 Worm   218 SLSPHSRDLFQRFIPISGTAHCDFAIRASENQAKIFREFAEFHGFSGRD--SSALFKWYQEQSPE 280

  Fly   481 QLLSVP-IRPPEFGF-AFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAA 543
            .|.:|. .:....|| .|.|::|      ||:.|    .|..:
 Worm   281 TLSNVKGYKKSISGFLTFIPNLD------GDFFP----KPLDE---------------------- 313

  Fly   544 GGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFF------SFNSGDVQYGIEADRRSRIL 602
                          :||.|..|    .:|.|||..|...      :|:..||  |:....:....
 Worm   314 --------------LRKEAPKK----QMMTGVTEYEGLMLASMNPAFSPADV--GLTLMPQGIYG 358

  Fly   603 KAYVRNTYTFHLNEIFATIVNEYTDWERPVQ-----HPINIRDETLEALSDAQV---VAPAAQTV 659
            |..|.|  ...:.:||         :|:.|:     ..:.:|.:..|||.|...   |..||:
 Worm   359 KDVVSN--PDEIQKIF---------YEKYVEGVDKSDELAMRKKLCEALGDEFFNVGVIQAAK-- 410

  Fly   660 DLHSADHRNS-YLYVFDY--QTRFGDYPQR---QGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTE 718
              ::|.|.|. |.|.|:|  ...||.:...   :..:|..:|.|:.|..:...|..     |:.:
 Worm   411 --NAAKHGNEVYFYTFEYVNPDSFGMWDGMMPFKAAVHCTELRYLLGEGVYSKFEP-----TEED 468

  Fly   719 ISLSEVVMFYWSNFVRTGNPNEQMET----EHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKL 779
            ..:.|.....:|||.:.||||.:..|    |..|.....|:..|.:              .|.::
 Worm   469 RKVMETTTTLFSNFAKYGNPNGKGATAEIWEKYSLNRPERHYRISY--------------PKCEM 519

  Fly   780 KNHYRAHRLSFWLNLIPDLHKPGGDN 805
            ::.|...|:.|       |.|..||:
 Worm   520 RDVYHEGRIQF-------LEKIDGDS 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	163/660 (25%)
		Aes	<313..>410	CDD:223730	39/99 (39%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	161/650 (25%)
		Aes	<103..>224	CDD:223730	46/163 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810