Protein Alignment Nlg3 and cest-32

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 161/683 - (23%)
• Similarity: 258/683 - (37%)
• Gaps: 190/683 - (27%)

  Fly   149 LPAQLSSRIINTRNGAISGVIVQLDGRHLDP-VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKK 212
            |..:.|..::|...|.:.|.|.    ||.|. |..|.|||:|..|:..|||..||.|..|:....
 Worm     8 LKPEASLEVLNASCGPVIGNIY----RHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLN 68

  Fly   213 ADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLP--YLQNQSEDCLYLNIYVPIQVGSRDS 275
            ..::.|.|||                .|.:  :..|||  |.:...::||.|||:.|
 Worm    69 CHKYGPGCPQ----------------SGHM--ISNLLPPGYREFAEDNCLNLNIFAP-------- 107

  Fly   276 SGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVL 340
                                      |..|....:|    .|::|:.||..:|....:.:|...|
 Worm   108 --------------------------SWKSEEFPNG----LPIMVYFHGGGFEIGFSSMFDDYSL 142

  Fly   341 AS---YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSIT 402
            :.   ...::|||.|||:|.|||:... |..|:  .||||.|...||.|::|:|.:|||:||.:|
 Worm   143 SGTLPLKDVIVVTANYRVGPLGFMTTG-DEVSR--GNYGLWDQTLALKWVQEHIKSFGGNPNIVT 204

  Fly   403 LAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK---YAAIVAHHVNCASD 464
            :.|...|......|  :::.....||:|.:.||||....:|:.:...:   :.....||.....|
 Worm   205 VCGTSAGGVSAGLL--ALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGYEGED 267

  Fly   465 LPHAHLMKCLREKTLDQLLSVPI---------RPPEFGF-AFGPSIDGVVIDGGDYVPPAP---- 515
                      .|..|:...|.|:         .....|| .|.|:.|      ||:. |.|
 Worm   268 ----------SESLLEWYKSQPLSKFQETATFEKKASGFLTFIPNFD------GDFF-PKPFDEL 315

  Fly   516 GSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEA 580
            ...|.:..|.|:.....|||                   .:.|.::..|.:   |::..
 Worm   316 SREAPKLDAMATVDEYEGLG-------------------FLTMFQSRRNDM---DIIKS------ 352

  Fly   581 FFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEA 645
              ||.|..|:..:  |.:.||::.|::|             :::..|..        :....::.
 Worm   353 --SFGSDVVENAV--DVQKRIMEFYMKN-------------IDKNDDKA--------VEKRLIQL 392

  Fly   646 LSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQR-----QGCIHGEDLPYIFGAPLVG 705
            :||:.....|.:||...:....|:||..|||.....:.|..     :...||.:|.|:.|.
 Worm   393 ISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYMLGE---- 453

  Fly   706 GFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKY 770
            |...|:.  .:.|..:.:::....:|||:.||||.....|             .|..| :..|.|
 Worm   454 GMGKFSP--IEEEFKVIDMMGTLTANFVKYGNPNGINGPE-------------LWKKY-TPEKPY 502

  Fly   771 LNFD---TKPKLKNHYRAHRLSFWLNLIPDLHK 800
            ..|.   .|.:::::::..|    |.|..|::|
 Worm   503 SYFKIDYPKSEMRDNFQDGR----LKLFEDINK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	156/667 (23%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	154/657 (23%)