Protein Alignment Nlg3 and cest-32

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 161/683 - (23%)
• Similarity: 258/683 - (37%)
• Gaps: 190/683 - (27%)

  Fly   149 LPAQLSSRIINTRNGAISGVIVQLDGRHLDP-VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKK 212
            |..:.|..::|...|.:.|.|.    ||.|. |..|.|||:|..|:..|||..||.|..|:....
 Worm     8 LKPEASLEVLNASCGPVIGNIY----RHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLN 68

  Fly   213 ADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLP--YLQNQSEDCLYLNIYVPIQVGSRDS 275
            ..::.|.|||                .|.:  :..|||  |.:...::||.|||:.|
 Worm    69 CHKYGPGCPQ----------------SGHM--ISNLLPPGYREFAEDNCLNLNIFAP-------- 107

  Fly   276 SGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVL 340
                                      |..|....:|    .|::|:.||..:|....:.:|...|
 Worm   108 --------------------------SWKSEEFPNG----LPIMVYFHGGGFEIGFSSMFDDYSL 142

  Fly   341 AS---YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSIT 402
            :.   ...::|||.|||:|.|||:... |..|:  .||||.|...||.|::|:|.:|||:||.:|
 Worm   143 SGTLPLKDVIVVTANYRVGPLGFMTTG-DEVSR--GNYGLWDQTLALKWVQEHIKSFGGNPNIVT 204

  Fly   403 LAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK---YAAIVAHHVNCASD 464
            :.|...|......|  :::.....||:|.:.||||....:|:.:...:   :.....||.....|
 Worm   205 VCGTSAGGVSAGLL--ALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGYEGED 267

  Fly   465 LPHAHLMKCLREKTLDQLLSVPI---------RPPEFGF-AFGPSIDGVVIDGGDYVPPAP---- 515
                      .|..|:...|.|:         .....|| .|.|:.|      ||:. |.|
 Worm   268 ----------SESLLEWYKSQPLSKFQETATFEKKASGFLTFIPNFD------GDFF-PKPFDEL 315

  Fly   516 GSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEA 580
            ...|.:..|.|:.....|||                   .:.|.::..|.:   |::..
 Worm   316 SREAPKLDAMATVDEYEGLG-------------------FLTMFQSRRNDM---DIIKS------ 352

  Fly   581 FFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEA 645
              ||.|..|:..:  |.:.||::.|::|             :::..|..        :....::.
 Worm   353 --SFGSDVVENAV--DVQKRIMEFYMKN-------------IDKNDDKA--------VEKRLIQL 392

  Fly   646 LSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQR-----QGCIHGEDLPYIFGAPLVG 705
            :||:.....|.:||...:....|:||..|||.....:.|..     :...||.:|.|:.|.
 Worm   393 ISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYMLGE---- 453

  Fly   706 GFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKY 770
            |...|:.  .:.|..:.:::....:|||:.||||.....|             .|..| :..|.|
 Worm   454 GMGKFSP--IEEEFKVIDMMGTLTANFVKYGNPNGINGPE-------------LWKKY-TPEKPY 502

  Fly   771 LNFD---TKPKLKNHYRAHRLSFWLNLIPDLHK 800
            ..|.   .|.:::::::..|    |.|..|::|
 Worm   503 SYFKIDYPKSEMRDNFQDGR----LKLFEDINK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	156/670 (23%)
		Aes	<313..>410	CDD:223730	36/99 (36%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	154/655 (24%)
		Aes	<104..>227	CDD:223730	43/165 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810