Protein Alignment Nlg3 and ges-1

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 157/696 - (22%)
• Similarity: 265/696 - (38%)
• Gaps: 185/696 - (26%)

  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221
            |:.|..|.:.|  ::.:|     .|.:..||:|.|||.:|||..||:...|..|..|.::...|
 Worm    19 IVETNYGKVEG--IEYEG-----AEVFLAIPFAKPPVDDLRFEKPVAPDPWEDVYPATQYRNDC- 75

  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGS 286
                           .|..||     :..:.....||||.|||..|.:.
 Worm    76 ---------------TPHYRL-----VAQFSSYSGEDCLTLNIIKPKKA---------------- 104

  Fly   287 SSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNS----GNPYDGSVLASYGQIL 347
                                       .|.|||.::||..||..|    |..:.....||.| ::
 Worm   105 ---------------------------EKLPVLFWIHGGGYEIGSASQHGYEFFAKRYASQG-VI 141

  Fly   348 VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAAC 412
            |.|:.||||.:||.:..|   |.:..|:||.|..|||.::|.||..||||||.||:.|:..|||.
 Worm   142 VATVQYRLGFMGFFSEGT---SDVQGNWGLFDQAAALEFVKSNIENFGGDPNQITIWGYSAGAAS 203

  Fly   413 VHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREK 477
            |..|..|....:.  :::||:||.|....|:...|..:.:..:|..:.|    |.....:|:::|
 Worm   204 VSQLTMSPYTRDS--YSKAIIMSASSFVGWATGPNVVETSKQLAEILGC----PWPGAKECMKKK 262

  Fly   478 TLDQLL-SVPIRPPEFGFAFGPSID----GVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGE 537
            :|.::. ::.::    |:..| :||    ..||| ||::...|
 Worm   263 SLHEIFDAIEVQ----GWTTG-TIDILRWSPVID-GDFMTKNP---------------------- 299

  Fly   538 AGIAAAGGWGTPGQLENIVL---MRKTAI---NKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEAD 596
                           |.::.   ::.|.|   ||...|.....:.|..|.|..:..|:. .::.:
 Worm   300 ---------------EELIKESPVKPTLIGMSNKEGSYFAALNMGRVIADFGLSPEDMP-KVDEE 348

  Fly   597 RRSRIL--KAYVRNTYTFHLNEIFATIVNEYTDWERPVQ-HPIN--IRDETLEALSDAQVVAPAA 656
            ..|.|:  |....|.|..:..:::..|::.|....:|.: ..:|  ..|...|.|||.....|..
 Worm   349 FISEIIGRKLLYNNRYGENREKVWNDILDFYVKQGKPAEVKDLNGFYVDRYSELLSDITFNVPIL 413

  Fly   657 QTVDLHSADHRNSYLYVFDYQTRFGDY----------PQRQGCIHGEDLPYIFGAPLVGGFNHFT 711
            :  ::.|...|.:.::.:    |...|          .|.:|..|..:..|:|..|::...:...
 Worm   414 R--EITSRVERKTPVWTY----RMDHYDKNIWKKHIPEQARGSPHANEYHYLFDMPVMAKIDMKK 472

  Fly   712 RNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHK-KYLNFDT 775
            ...:..:..|.::|:    :|.:||.|  |:|             .:||........ .:||..:
 Worm   473 EPDSWIQNDLIDMVI----SFAKTGVP--QIE-------------DVEWRPVSDPDDVNFLNIRS 518

  Fly   776 K-PKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDED 820
            . ..:::......|:||..|   ..:.|.|.:...:..:|..:.::
 Worm   519 DGVSIEHGLFQEPLAFWNEL---RQREGFDLIDPTNSAMHSSNKDE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	151/665 (23%)
ges-1	NP_503411.1	COesterase	16..535	CDD:395084	151/665 (23%)