Protein Alignment Nlg3 and cest-5.1

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 711
• Identity: 151/711 - (21%)
• Similarity: 245/711 - (34%)
• Gaps: 265/711 - (37%)

  Fly   155 SRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPV 219
            |.||:|..|       .|:|..:.....::.||:|.||||||||..|.:|..|.|::.|..:.|.
 Worm    18 SLIIHTSFG-------HLEGAEIGDYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPA 75

  Fly   220 C---------PQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDS 275
            |         ||:..|                              ||||::||:
 Worm    76 CMSNSSKTKSPQKWVD------------------------------EDCLHVNIF---------- 100

  Fly   276 SGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVL 340
                                       ||.....|.:.|   :.|::||....::|...::.:||
 Worm   101 ---------------------------TSKKCLKSRNCA---IAVYIHGGGLTYDSAVMFNDTVL 135

  Fly   341 AS---YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSIT 402
            ..   ...:::|...:|||:......:....:  |.|..|.||..||.::|..|.:|||:...||
 Worm   136 LDTFVKRDVILVIPGFRLGIFSHFTVHNQNVA--PNNLALYDITLALEFVKSEIHSFGGNSQKIT 198

  Fly   403 LAGHGTGAACVHFLISSMAVPEGL-LFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHV------- 459
            |.||..|......:..|..:...| ||.:||:|||            ..|...:..|:
 Worm   199 LFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSG------------GFYFEELKDHIEGTKRFV 251

  Fly   460 ---NCASDL----------PHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYV 511
               ||:..|          ...::||||::.:..:||.:.....:.|:   |...||:
 Worm   252 EYANCSVPLKLERKMERSQQEMYMMKCLQKLSGMELLRIQRLLEDKGY---PDFGGVI------- 306

  Fly   512 PPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDL----- 571
                                                          :|:.....:.:::|
 Worm   307 ----------------------------------------------LREPLFPDVKKFELLKSPK 325

  Fly   572 ----MAGVTRAEAFFSFNSGDVQYG--IEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWER 630
                :.|.|..|  |...|..|.:|  :|.:......:.| ||                  |.|.
 Worm   326 NIPMLTGCTNLE--FDHESIKVPFGKYLEFENPDECDEKY-RN------------------DVES 369

  Fly   631 PVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDL 695
            .|::..|..|:|      ..::.|.  .:.:::....|...|:::|     .||:...  |.:||
 Worm   370 GVENRGNHTDKT------QGIILPL--KLQINNLLENNVTAYLYEY-----TYPKHGR--HTDDL 419

  Fly   696 PYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNP------NEQMETEH-------- 746
            .||.|.      :.|.::  :.|:.|.:|......||::.|.|      :||.|:.:
 Worm   420 SYIMGV------HAFEKD--ENEVHLEQVYKDMVINFIKLGEPGMGFEKSEQNESTYFDIYWNET 476

  Fly   747 -GSRQERSRYKTIEWTAYESVHKKYLNFD-----TKPKLKNHYRAHRLSFWLNLIPDLHKP 801
             |.|....:|...|.|.|..  |:.:.||     ||.|||      ::|  |..:|.:.||
 Worm   477 TGERPRMRKYFEKEVTDYWL--KEMIEFDQKVTETKKKLK------QIS--LKTVPFIEKP 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	147/699 (21%)
		Aes	<313..>410	CDD:223730	28/99 (28%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	136/666 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900