Protein Alignment Nlg3 and ace-4

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 727
• Identity: 161/727 - (22%)
• Similarity: 253/727 - (34%)
• Gaps: 246/727 - (33%)

  Fly   157 IINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCP 221
            ::.|:.|.|.|.......:   .:..:.|:|:|.|.|.:.||..|.....|.|:..|.:.:..|.
 Worm    28 VLETKLGDIKGTEFFFLSK---KIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDATKPANACF 89

  Fly   222 QRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGS 286
            | ..|.:|.:.....|.....:.           |||||||||:.|
 Worm    90 Q-TRDNYNTSFWGSEMWNANTQI-----------SEDCLYLNIWAP------------------- 123

  Fly   287 SSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNP----YDGSVLASYGQIL 347
                                    .......|:|:..|..:  .||:|    |||..|.|...::
 Worm   124 ------------------------ADAYNLTVMVWFFGGGF--YSGSPSLSIYDGKALTSTQNVI 162

  Fly   348 VVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAAC 412
            ||.||||||..|||...   :...|.|.||:|...||||:::||.:|||:|:.:.:.|...|||.
 Worm   163 VVNINYRLGPFGFLYLG---HPDAPGNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFGQSAGAAS 224

  Fly   413 VHFLISSMAVPEGL-LFNRAILMSGSGLAPWSLVS--NPAKYAAIVAHHVNCASDLPHAHLMKCL 474
            :   ::.:..|... ||..|||.|||....|::.|  ...:.:..:...|.|........ |.||
 Worm   225 I---VAHLIAPGSRGLFKNAILQSGSLENTWAINSPFRAKQKSEKLLELVGCNKTTVDTS-MACL 285

  Fly   475 REKTLDQL----LSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLG 535
            |..:.:||    .::.:...||.|        |::....:.
 Worm   286 RLVSPEQLSLSTWNISLTYLEFPF--------VIVSRDKHF------------------------ 318

  Fly   536 GEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFF--------SFNSGD---- 588
                         .|.|:....:|:...|:  ..:||.|:.:.|..:        .|:..|
 Worm   319 -------------FGHLDAHAALREGDFNR--DVNLMIGMNKDEGNYWNIYQLPQFFDKADPPEL 368

  Fly   589 --VQYGIEADRRSRILKAYVRNT-------------------YTFHLNEIFATIVNEY-----TD 627
              .::....||...|....:|:.                   |...:|:    ||.:|     :.
 Worm   369 NRTEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTDHGRKTRFYAGQMNQ----IVGDYFFSCDSL 429

  Fly   628 WERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNS---YLYVFDYQTRFGDYPQRQGC 689
            |                 |:|.....|..::    |:..|..   ::|.|...:....:|:..|.
 Worm   430 W-----------------LADQFRSIPRVKS----SSPQRKPGKVFVYHFTQSSSANPWPKWTGA 473

  Fly   690 IHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNP--------------NE 740
            :||.::.|:||.||     .:::||.:.|...|..:|.:|::|.:.|.|              ||
 Worm   474 MHGYEIEYVFGIPL-----SYSKNYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSEHWPEFNE 533

  Fly   741 Q-----METEHGSR------------QERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRL 788
            |     |:...||.            |...|.|..|:|||               |...|.:..|
 Worm   534 QNHYRWMQLRSGSNIRPIKPKKQVECQFWRRVKDTEYTAY---------------LTQEYSSSSL 583

  Fly   789 ---SFWLNL-IP 796
               |:||.| ||
 Worm   584 TTYSYWLLLYIP 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	156/719 (22%)
		Aes	<313..>410	CDD:223730	38/100 (38%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	146/677 (22%)
		Aes	<120..>243	CDD:223730	47/173 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910