Protein Alignment Nlg3 and Ces2c

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 184/656 - (28%)
• Similarity: 278/656 - (42%)
• Gaps: 155/656 - (23%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEA----YRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            ||.|..|..|.:.|   :||  |:...:|    :.|||:|..|||.|||.||.....||||:...
  Rat    32 SSSIRTTHTGQVRG---KLD--HVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGT 91

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            ....:|.|.: |:.:|..         |..:|.:|..:. .||||||||||.|
  Rat    92 SHPAMCLQNI-DMLDEVG---------LTDMKMILSSIP-MSEDCLYLNIYTP------------ 133

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG 344
                                      :.|..||  ..||:|.:||.:......:..|||:||...
  Rat   134 --------------------------AHAHEGS--NLPVMVCIHGGALVIGMASMCDGSLLAVNE 170

  Fly   345 QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTG 409
            .::||.|.||||||||.:.. |.:::  .|:|.:|.:|||.|:::|||.|||:||.:|:.|...|
  Rat   171 DLVVVAIQYRLGVLGFFSTG-DEHAR--GNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAG 232

  Fly   410 AACV-HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK-YAAIVAHHVNC-ASDLPHAHLM 471
            ...| ..:||.|:  :| ||:.||:.||..|.| .|:|..:: .:..||....| |:|  ...|:
  Rat   233 GTSVSSHVISPMS--QG-LFHGAIMESGVALLP-DLISETSETVSTTVAKLSGCEATD--SETLV 291

  Fly   472 KCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGG 536
            :|||.|:..::|.:     ...|...|:    |:| |:::|..|....|......
  Rat   292 RCLRAKSGAEILVI-----NKVFKMIPA----VVD-GEFLPRHPKELLASEDFHP---------- 336

  Fly   537 EAGIAAAGGWGTPGQLENIVLMRKTA--INKLSRYDLMAGV--TRAEAFFSFNSGDVQYGIEADR 597
               :.:..|..|......|.::..||  |.:|||.:|.|.:  |.|:.......||:
  Rat   337 ---VPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDL-------- 390

  Fly   598 RSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLH 662
               :::.|:.||                       ..|..::.:..|.:.|...|.||.|.....
  Rat   391 ---LMEEYMGNT-----------------------DDPQTLQIQYAEMMGDFLFVIPALQVAHFQ 429

  Fly   663 SADHRNSYLYVFDYQTRF--GDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVV 725
            .: |...|.|.|.:...:  ...|......|.:::|::||:...|    ...::|:.|..||..:
  Rat   430 RS-HAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWG----IKVDFTEEEKLLSRRM 489

  Fly   726 MFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSF 790
            |.||:||.|.||||          .|...|    |...:. .::||..||:|.:....:|.||.|
  Rat   490 MKYWANFARHGNPN----------SEGLPY----WPVLDH-DEQYLQLDTQPAVDRALKARRLQF 539

  Fly   791 WLNLIP 796
            |...:|
  Rat   540 WTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	181/649 (28%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	181/649 (28%)