Protein Alignment Nlg3 and Ces3b

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_653094.2
• Gene: Ces3b / 13909
• MGIID: 3644960
• Length: 571
• Species: Mus musculus
• Alignment Length: 643
• Identity: 169/643 - (26%)
• Similarity: 250/643 - (38%)
• Gaps: 176/643 - (27%)

  Fly   180 VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEY 244
            |..:.|||:|..|||.|||..|:....|.||:.|....|:|.|.:..:.|....|....|
Mouse    60 VNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIK----- 119

  Fly   245 LKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAG 309
               :.|.    |||||.||||.|.::.:.|
Mouse   120 ---IFPI----SEDCLTLNIYSPTEITAGD----------------------------------- 142

  Fly   310 SGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPAN 374
                 |.||:|::||.|....|....|||.||:||.::|||:.||||:.|||:.. |::  :|.|
Mouse   143 -----KRPVMVWIHGGSLLVGSSTSQDGSALAAYGDVVVVTVQYRLGIFGFLSTG-DKH--MPGN 199

  Fly   375 YGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSG--- 436
            .|.:|::|||.|::.|||.||||||.:|:.|:..|...|..|..| .:..| ||:|||..||
Mouse   200 RGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGMIVSSLFLS-PISAG-LFHRAISQSGIVT 262

  Fly   437 ----SGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFG 497
                ..:.||....|       .|:.|.|.|..| |.|::||.:|....|:...          .
Mouse   263 TIMMEDMKPWPEAQN-------FANSVACGSASP-AELVQCLLQKEGKDLIKQK----------N 309

  Fly   498 PSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTA 562
            .:|..:|.|  .:.|..|....|..|.............|.      ||..   |:::.::.|
Mouse   310 VNISYIVND--SFFPQRPEKLLADQQFPTVPYLLGVTNHEF------GWLL---LKSLNILDK-- 361

  Fly   563 INKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTD 627
            :..|||.||:                        ..||...|.:...     .||..|:::||.|
Mouse   362 LEHLSREDLL------------------------EISRPFLAIMEVP-----PEIMPTVIDEYLD 397

  Fly   628 WERPVQHPINIRDETL------EALSDAQVVAPAAQTVDLHSADHRNSYL-------YVFDYQ-- 677
                     |..|::.      |.|.|...:.|   |::.      :.||       :::::|
Mouse   398 ---------NGSDQSATRYAFQELLGDISFIIP---TLNF------SKYLRDAGCPVFLYEFQHT 444

  Fly   678 -TRFGDY-PQRQGCIHGEDLPYIFGAPLVGGFNHFTR--NYTKTEISLSEVVMFYWSNFVRTGNP 738
             :.|..: |......|..:..::||.|.:...:....  ..|:.|..||..:|..||.|.|||||
Mouse   445 PSSFAKFKPAWVKADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNP 509

  Fly   739 NEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIP 796
            |.:              ....|.....: ::||....:.:.....:..||.||...:|
Mouse   510 NGK--------------GLPPWPQLNQL-EQYLEIGLESRTGVKLKKGRLQFWTETLP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	166/636 (26%)
		Aes	<313..>410	CDD:223730	45/96 (47%)
Ces3b	NP_653094.2	COesterase	36..547	CDD:278561	166/636 (26%)
		Aes	75..>245	CDD:223730	75/225 (33%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810