Protein Alignment Nlg3 and LOC1281357

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_061497244.1
• Gene: LOC1281357 / 1281357
• VectorBaseID: AGAMI1_013672
• Length: 1268
• Species: Anopheles gambiae
• Alignment Length: 1222
• Identity: 345/1222 - (28%)
• Similarity: 507/1222 - (41%)
• Gaps: 383/1222 - (31%)

  Fly   118 TSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDGRHLDP--V 180
            |..:|:.      |....|.:|..|           |:.::.|:.|.:.|::.:     ..|  |
Mosquito    37 TGVAGTG------PGPATSLNNITY-----------SNSLVKTKYGPLRGIVFR-----TVPVVV 79

  Fly   181 EAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIH-NETAALERMPKGRLEY 244
            |.:.|:||||||:|:||:||||:.:.|...:..|||:|||||:||.:. .:...|..:|..||:.
Mosquito    80 EGFLGVPYASPPIGSLRYMPPVTPSTWKAPRLVDRFAPVCPQKLPKLDGTDAGVLGDLPIDRLKQ 144

  Fly   245 LKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAG 309
            |:||:|.|.||||||||||:|||                                   .:..:|.
Mosquito   145 LRRLVPTLVNQSEDCLYLNLYVP-----------------------------------HAEDTAH 174

  Fly   310 SGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPAN 374
            .....| |.:|::|||||||||||.||||.||..|.::|||||:||||||||  .|........|
Mosquito   175 RPDHLK-PSIVYIHGESYEWNSGNHYDGSTLAMNGNVIVVTINFRLGVLGFL--KTGAKGSAQGN 236

  Fly   375 YGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFL-ISSMAVPEGLLFNRAILMSGSG 438
            :||||::|.||||:||:.||||||..|||.|||||||..:.| :|.:|   |.|.:|.:|:|||.
Mosquito   237 FGLMDLVAGLHWLRENLVAFGGDPAKITLMGHGTGAALANILAVSPVA---GDLIHRVVLLSGSA 298

  Fly   439 LAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGV 503
            |:||::..:|......||...:|..|:.:..|..|||.|:|.:|:::.:..|.|...|.|.:||.
Mosquito   299 LSPWAIQRDPLSVKRKVAQQTSCTGDVVNEDLAPCLRTKSLAELMNISLSSPRFLPGFAPFVDGT 363

  Fly   504 VIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSR 568
            ||                ..|:|:......:..::.||:..|               ...:...:
Mosquito   364 VI----------------TPAKAAVINNLKIPTDSAIASTSG---------------IEFSNFHK 397

  Fly   569 YDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQ 633
            .|::.|:|..|::....:.|:::|....:|.|||:.:|||||.:|||||::.:.||||:|||..:
Mosquito   398 QDVLFGLTTYESYLELTAADLEFGFNETKRDRILRTFVRNTYRYHLNEIYSALKNEYTNWERSPR 462

  Fly   634 HPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYI 698
            .....||..||.|||....||..|...|||.....||...|.:|:....:|||.|.:.|||:|:.
Mosquito   463 SAYGYRDAVLELLSDGLTAAPLVQLSHLHSLQGGRSYFLHFKHQSHEWKFPQRTGSVRGEDVPFA 527

  Fly   699 FG---APLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPN--------------------- 739
            .|   :|:      |....|:.::.:|..||.|..|||:|||||
Mosquito   528 LGFSPSPM------FPLTLTRLDMQVSSTVMRYLCNFVKTGNPNGLRTPRMDVFVNSNNKRSWNP 586

  Fly   740 ----------------------------------------------------------------- 739
                                                                             
Mosquito   587 AKKPHNETLMRQLVSSFRQQDPPPQPRNPLPGMPAQPLLTPEQALMQQQLQQYYRKEQQSARQPK 651

  Fly   740 --------------------------------------------------EQMETEHGSRQE--- 751
                                                              |:.|.|:|.|::
Mosquito   652 HSRRKRTRFSNDLQRYGSSEGAAYGSSEEAGTLGGSNGNGGRGGDDEDDEEEEEEENGDRRDGGE 716

  Fly   752 -------------------RSRYKTIE-----WTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWL 792
                               .|.:.||:     |..|::.::.::...::...|:|||.|:||.||
Mosquito   717 SGGRSETEPSYYSVDSDYVYSGFTTIKYNLPFWGHYDTTNQVFMEIGSQVVPKSHYRGHKLSLWL 781

  Fly   793 NLIPDLHKPGGDNVP---AAHHQLHDDDDEDNNIPSDASVKP--LNPPYI---------SRAANA 843
            :|||.||  ...|:|   ..||..    .|:|.:..|..|:.  :.||.:         |:....
Mosquito   782 SLIPQLH--SSFNIPELSMRHHHF----SEENPMFYDGLVREQIIEPPLMHIGFVTSTTSKMHKT 840

  Fly   844 AAMANFTIFTN------QVFSLLNLSSPSSSLQRNG--TRYG-GGKIYPDDMMDGDHAGGAASAS 899
            ..:|: ||..:      ...:.:..:|.|..|..:.  |::| ..:...:.:.:..|
Mosquito   841 ETIAS-TILQSISTECPPNITFIQTASASWPLHNSALPTQHGDSNRSLINRLTNSYH-------- 896

  Fly   900 QDSDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQENGQMPNNIC 964
                  .:|||||::||.:||.||.||||||..:||||:             ||:.|.:|..|:.
Mosquito   897 ------RSYSTALAITIGVGCFLLFLNVLIFVAIYYQRE-------------KRESNSRMKINLL 942

  Fly   965 GDLET-LTIHAKSDPATILSHHHA----------MQHHQLPPPEFADIPHRAPPPPKHMK----- 1013
             :||: |.:...|..|...:...|          ......|||...|     ..|..|.|
Mosquito   943 -ELESRLNVVESSSGAVAAAAAAAAAASGEVKEETSFSVAPPPHQED-----DGPASHTKGAPLR 1001

  Fly  1014 ------------SLQDPGGGGSVSGAVGVSGVVQMPPPHALQVMGNQCGTLTKKSCMKQTQAQAQ 1066
                        :...||||   ||...:..:.....||   ..|:...|     .|:::...|.
Mosquito  1002 VASSASSTTATSAKAAPGGG---SGPNSIQTIELSLTPH---YHGHGHAT-----SMRRSSTSAI 1055

  Fly  1067 QHSPAQQQQQQQQQQQQHVVTHQQHLQNHHNQSMT---TVLTTAGGLVVPTP 1115
            :||...:.||||||        ||||.:||..|.:   ||......:|.|.|
Mosquito  1056 KHSHKCELQQQQQQ--------QQHLYHHHQSSCSSNRTVSPKKVSIVSPNP 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	241/806 (30%)
LOC1281357	XP_061497244.1	None