Protein Alignment Nlg3 and LOC1273785

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_061503228.1
• Gene: LOC1273785 / 1273785
• VectorBaseID: AGAMI1_001061
• Length: 1098
• Species: Anopheles gambiae
• Alignment Length: 1173
• Identity: 468/1173 - (39%)
• Similarity: 612/1173 - (52%)
• Gaps: 316/1173 - (26%)

  Fly   151 AQLSSRIINTRNGAISGVIVQLDG-RHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            ::|.:||:.||.|.:.|:::.||| :.|.|:||:.|:|||:||....||.|..:.:.|.|::.||
Mosquito    31 SRLGNRIVQTRYGRLQGLVLPLDGYKFLKPIEAFLGVPYATPPTKMNRFSPTRTPSPWDGIRIAD 95

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            :||||||||||:::||||||::||||||||||||||:||||||||||||::.|:.....|.
Mosquito    96 KFSPVCPQRLPNVNNETAALDKMPKGRLEYLKRLLPFLQNQSEDCLYLNVFAPVHATQSDK---- 156

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG 344
                                               |.||:||:||||:||||||||||:|||||.
Mosquito   157 -----------------------------------KLPVIVFLHGESFEWNSGNPYDGTVLASYS 186

  Fly   345 QILVVTINYRLGVLGFLNAN-TDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGT 408
            .::|||:|||||:||||||| :.:.....|||||||.:|||||:::|||.|||||.::||||||:
Mosquito   187 DLVVVTLNYRLGILGFLNANPSPQLRARVANYGLMDQMAALHWVQQNIAKFGGDPATVTLAGHGS 251

  Fly   409 GAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCA--SDL--PHAH 469
            ||||::||::|..:..| ||:||||:|||..:.|:||.:|..||..:|..|||:  .||  .|..
Mosquito   252 GAACINFLMTSPTMVPG-LFHRAILLSGSAYSSWALVEDPVVYALKLAKEVNCSIPEDLIKNHEQ 315

  Fly   470 LMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGG------DYVPPAPGSPAAQAQAQAST 528
            ::.|||:..|::|....|:||.|..|||||:|||||..|      |.:|....|..:|
Mosquito   316 IVDCLRDVPLEELFGADIQPPSFLSAFGPSVDGVVIRPGRSNQDIDELPVRGTSKRSQ------- 373

  Fly   529 AAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGI 593
                   |.||                            ||||:.||...||.:.|::.|:|.|.
Mosquito   374 -------GAAG----------------------------RYDLLFGVVTGEALWRFSAADIQSGF 403

  Fly   594 EADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQT 658
            |.:||.:||:.||||.||:||:|||.|:|||||||||.||||||:||..:.||||||.|||...|
Mosquito   404 EGERRDKILRTYVRNAYTYHLSEIFYTVVNEYTDWERTVQHPINMRDAAVSALSDAQFVAPLVHT 468

  Fly   659 VDL---------HSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNY 714
            .|:         ........:.|||||||:.||||||.|.:|||||||:||||||.|||||.|||
Mosquito   469 GDMLAPPPPLPGQEPSGPKCFFYVFDYQTKDGDYPQRMGTVHGEDLPYVFGAPLVDGFNHFPRNY 533

  Fly   715 TKTEISLSEVVMFYWSNFVRTGNPNE--QMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKP 777
            ||:|::|||.:|.||:||.|||||||  :.::...:.:||:|:::|.|..|:.||:|||....||
Mosquito   534 TKSEVALSEALMVYWANFARTGNPNEHHRQDSILAASRERNRFRSINWEEYDPVHQKYLEIGMKP 598

  Fly   778 KLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDED---NNIPSDASVKPLNPPYISR 839
            ::|||:|||:||.||.|||:|||.|.::|.|.|:...:.||.|   ..:..|:....||  |:..
Mosquito   599 RMKNHFRAHQLSIWLRLIPELHKAGMEDVIARHNLFKNHDDMDLYEGLVKPDSFAGRLN--YLED 661

  Fly   840 AANAAAM-----------ANFTIFTNQVFSLL------NLSS--PSSSLQRNGTRYGGGKIYPDD 885
            ......|           ||..:.|.:...|.      |.|:  |::::....|
Mosquito   662 NLKRRGMLTGGELGHALHANVVMTTAEPVLLTTCMPVGNYSALVPTATILNATT----------- 715

  Fly   886 MMDGDHAGGAASASQDSDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTK 950
                |...|..:|     |:|||||||||||||||||||||||||||||||||||||.....|.:
Mosquito   716 ----DTLAGLEAA-----GYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKSLQKQ 771

  Fly   951 LKRQENGQMPNNICGDLETLTIHAKS--DPATILSHHHAMQHHQLPPPEFADIPH---------- 1003
            .:::..|              :|.:.  ||   :.|.|....|........|:.:
Mosquito   772 YQQRGGG--------------LHQQGPFDP---IKHAHYHLGHSQSANVIVDVENHDTGALILAG 819

  Fly  1004 --RAPPPPKH----------MKSLQDPGGG---GSVSG-------AVGVSG-------------- 1032
              ::|    |          ||| ..||||   |.|.|       .|||.|
Mosquito   820 DVKSP----HICTNAMQISVMKS-GSPGGGVGHGGVDGRGNGGGNVVGVGGNGVGGGGGGGGGGD 879

  Fly  1033 ----------VVQMP-------------PPHALQV---------MGNQCG-----------TLTK 1054
                      |.:||             ||.:..:         :|:..|           ||.|
Mosquito   880 ATSCNVPAPNVTKMPLQANNNAYGTAKLPPRSEHIAIPIKNSTFIGSGTGTGGGTFVSGMMTLPK 944

  Fly  1055 KSCMKQTQAQAQQHSPAQQQQQQQQQQQQHVVTHQQHLQNHHNQSMTTVLTTAG-GL-------- 1110
            .|              :|||||||||||.|:     .:..:.|:.||......| ||
Mosquito   945 PS--------------SQQQQQQQQQQQVHI-----PMSYNRNECMTLPRNIGGTGLSASSAGPN 990

  Fly  1111 ----VVPTPPT----------------------VPVIVASTTQHQQHQQQHQQQQHQQQQQQQQQ 1149
                .:..||.                      .|:..|.:..|..|.|..|||..|||.|||||
Mosquito   991 ADVQQIKLPPNGTAIGIHMRAAQTCSSGSPENRPPLHTAHSHHHSHHGQHGQQQLQQQQHQQQQQ 1055

  Fly  1150 QHP 1152
            |||
Mosquito  1056 QHP 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	323/659 (49%)
LOC1273785	XP_061503228.1	None