Protein Alignment Nlg3 and Ces1g

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 688
• Identity: 183/688 - (26%)
• Similarity: 288/688 - (41%)
• Gaps: 191/688 - (27%)

  Fly   143 SPNHDQLPAQLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMW 207
            |..|..||.     :::|.:|.:.|..|.|:| ...||..:.|:|:|.||:|:|||.||..|..|
Mouse    16 SLGHPSLPP-----VVHTVHGKVLGKYVTLEG-FSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPW 74

  Fly   208 SGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYL----KRLLPYLQNQSEDCLYLNIYVPI 268
            |.||....:.|:|.|      |..|||      ||..|    ::::|:  ..||||||||||.|.
Mouse    75 SFVKHTTSYPPLCYQ------NPEAAL------RLAELFTNQRKIIPH--KFSEDCLYLNIYTPA 125

  Fly   269 QVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGN 333
            .:                                |.:|        :.||:|::||.....:..:
Mouse   126 DL--------------------------------TQNS--------RLPVMVWIHGGGLVIDGAS 150

  Fly   334 PYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDP 398
            .|||..||.:..::||.|.||||:.||.:.. |.:|:  .|:|.:|.:|||||:::|||.|||:|
Mouse   151 TYDGVPLAVHENVVVVVIQYRLGIWGFFSTE-DEHSR--GNWGHLDQVAALHWVQDNIANFGGNP 212

  Fly   399 NSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKY-------AAIVA 456
            .|:|:.|...|...|..|:.|.....  ||:|||..|       |::.||..:       |..:|
Mouse   213 GSVTIFGESAGGESVSVLVLSPLAKN--LFHRAIAQS-------SVIFNPCLFGRAARPLAKKIA 268

  Fly   457 HHVNCASDLPHAHLMKCLREKTLDQLLSVPIR----------PPEFGFAFGPS-IDGVVIDGGDY 510
            ....|.: ...|.::.|||:||.|:||.|.::          .|...:.|.|: ||||::
Mouse   269 ALAGCKT-TTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLL----- 327

  Fly   511 VPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGV 575
             |.||                                     |.|:     |....:....|.|:
Mouse   328 -PKAP-------------------------------------EEIL-----AEKSFNTVPYMVGI 349

  Fly   576 TRAE------AFFSFNSGDVQYGIEADRRSRIL-KAYVRNTYTFHLNE-IFATIVNEYTDWERPV 632
            .:.|      .|..|...:.:  ::....:.|| :||.    ..:::| :....:.:|..   ..
Mouse   350 NKHEFGWIIPMFLDFPLSERK--LDQKTAASILWQAYP----ILNISEKLIPAAIEKYLG---GT 405

  Fly   633 QHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRN----SYLYVFDYQTRF--GDYPQRQGCIH 691
            :.|..:.|..|:.:.|.....|:.    :.|..||:    :|:|.:.|:..|  .|.||.....|
Mouse   406 EDPATMTDLFLDLIGDIMFGVPSV----IVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLGDH 466

  Fly   692 GEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYK 756
            .::|..::|||.:      ....::.||:||::||.:|:||.|.||||.: ...|
Mouse   467 ADELFSVWGAPFL------KEGASEEEINLSKMVMKFWANFARNGNPNGE-GLPH---------- 514

  Fly   757 TIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNL 794
               |..|:. .:.||......:..:..:...:.||..|
Mouse   515 ---WPEYDQ-KEGYLQIGVPAQAAHRLKDKEVDFWTEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	176/675 (26%)
		Aes	<313..>410	CDD:223730	39/96 (41%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	176/675 (26%)
		Aes	<121..>239	CDD:223730	48/162 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832418
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740