Protein Alignment Nlg3 and Ces1d

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 671
• Identity: 179/671 - (26%)
• Similarity: 283/671 - (42%)
• Gaps: 174/671 - (25%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSP 218
            |..::||..|.:.|..|.|:| ...||..:.|:|:|.||:|:|||.||..|..||.||....:.|
Mouse    22 SPPVVNTVKGKVLGKYVNLEG-FTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPP 85

  Fly   219 VCPQR------LPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSG 277
            :|.|.      |.::.  |...|.:|   |::           ||||||||||.|..:
Mouse    86 MCSQDAVGGQVLSELF--TNRKENIP---LQF-----------SEDCLYLNIYTPADL------- 127

  Fly   278 SSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLAS 342
                                     |.:|        :.||:|::||........:.|||..|::
Mouse   128 -------------------------TKNS--------RLPVMVWIHGGGLVVGGASTYDGLALSA 159

  Fly   343 YGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHG 407
            :..::||||.||||:.||.:.. |.:|:  .|:|.:|.:|||.|:::|||.|||:|.|:|:.|..
Mouse   160 HENVVVVTIQYRLGIWGFFSTG-DEHSR--GNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGES 221

  Fly   408 TGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMK 472
            .|...|..|:.|.....  ||:|||..||..|....:.::....|.:||....|.: ...|.::.
Mouse   222 AGGFSVSVLVLSPLAKN--LFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKT-TTSAVMVH 283

  Fly   473 CLREKTLDQLLSVPIR----------PPEFGFAFGPS-IDGVVIDGGDYVPPAPGSPAAQAQAQA 526
            |||:||.|:||...::          .|:..:.|.|: |||||:      |.||....|: ::.:
Mouse   284 CLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVL------PKAPEEILAE-KSFS 341

  Fly   527 STAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQY 591
            :.....|:..:     ..||..|               .|..|.|..|
Mouse   342 TVPYIVGINKQ-----EFGWIIP---------------TLMGYPLAEG----------------- 369

  Fly   592 GIEADRR---SRILKAYVRNTYTFHLNEIFATIVNEY----TDWERPVQHPINIRDETLEALSDA 649
              :.|::   |.:.|:|.    |..::|....:|.|.    ||      .....:|...:.::|.
Mouse   370 --KLDQKTANSLLWKSYP----TLKISENMIPVVAEKYLGGTD------DLTKKKDLFQDLMADV 422

  Fly   650 QVVAPAAQTVDLHSADHR----NSYLYVFDYQTRFGDYPQRQGCI--HGEDLPYIFGAPLVGGFN 708
            ....|:.    :.|..||    ::|:|.|:|:..|....:.:..|  ||:::..:||:|.:
Mouse   423 VFGVPSV----IVSRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGDHGDEIFSVFGSPFL---- 479

  Fly   709 HFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNF 773
              ....::.|.:||::||.:|:||.|.||||       |....       .|..|:. .:.||..
Mouse   480 --KDGASEEETNLSKMVMKFWANFARNGNPN-------GGGLP-------HWPEYDQ-KEGYLKI 527

  Fly   774 DTKPKLKNHYRAHRLSFWLNL 794
            ....:.....:...:|||..|
Mouse   528 GASTQAAQRLKDKEVSFWAEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	176/666 (26%)
Ces1d	NP_444430.2	COesterase	22..545	CDD:395084	176/666 (26%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565