Protein Alignment Nlg3 and Ces2

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001258232.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 186/654 - (28%)
• Similarity: 284/654 - (43%)
• Gaps: 151/654 - (23%)

  Fly   154 SSRIINTRNGAISGVIVQLDGRHLDPVEA----YRGIPYASPPVGNLRFMPPVSAAMWSGVKKAD 214
            ||.|..|..|.:.|   :||  |:...:|    :.|||:|.||||.|||.||.....||||:.|.
  Rat    32 SSPIRTTHTGQVQG---KLD--HVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEPPEPWSGVRDAT 91

  Fly   215 RFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSS 279
            ....:|.|.| ||.:|...|:         :|.:|..: :.||||||||:|.|
  Rat    92 SQPAMCLQNL-DILDEVGLLD---------MKMILSSI-SMSEDCLYLNVYAP------------ 133

  Fly   280 SSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYG 344
                                      :.|..||  ..||:|::||.:......:.||||:|....
  Rat   134 --------------------------AHAREGS--NLPVMVWIHGGALVVGMASMYDGSLLTVNE 170

  Fly   345 QILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTG 409
            .::||||.||||||||.:.. |.:::  .|:|.:|.:|||.|:::|||.|||:||.:|:.|...|
  Rat   171 DLVVVTIQYRLGVLGFFSTG-DEHAR--GNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAG 232

  Fly   410 AACV-HFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKC 473
            ...| ..:||.|:  :| ||:.||:.||..|.| .|:|..::..:.....::....:....|::|
  Rat   233 GTSVSSHVISPMS--QG-LFHGAIMESGVALLP-DLISETSETVSTTVAKLSGCEAMDSEALVRC 293

  Fly   474 LREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEA 538
            ||.|:..::|.:     ...|...|:    |:| |:::|..|....|......
  Rat   294 LRAKSGAEILVI-----NKVFKMIPA----VVD-GEFLPRHPKELLASEDFHP------------ 336

  Fly   539 GIAAAGGWGTPGQLENIVLMRKTA--INKLSRYDLMAGV--TRAEAFFSFNSGDVQYGIEADRRS 599
             :.:..|..|......|.::..||  |.:|||.:|.|.:  |.|:.......||:
  Rat   337 -VPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDL---------- 390

  Fly   600 RILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSA 664
             :::.|:.||      :...|:..:||                 |.:.|...|.||.|......:
  Rat   391 -LMEEYMGNT------DDSQTLQIQYT-----------------EMMGDFLFVIPALQVAHFQRS 431

  Fly   665 DHRNSYLYVFDYQTRF--GDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMF 727
             |...|.|.|.:...:  ...|......|.:::|::||:    .|:....::|:.|..||..:|.
  Rat   432 -HAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGS----FFSGMKLDFTEEERLLSRRMMK 491

  Fly   728 YWSNFVRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWL 792
            ||:||.|.||||          .|...|    |.|.:. .::||..||.|.:....:|.||.||.
  Rat   492 YWANFARQGNPN----------SEGLPY----WPALDH-DEQYLQLDTHPAVDRALKARRLQFWT 541

  Fly   793 NLIP 796
            ..:|
  Rat   542 KTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	183/647 (28%)
		Aes	<313..>410	CDD:223730	40/96 (42%)
Ces2	NP_001258232.1	COesterase	31..540	CDD:278561	183/647 (28%)
		Aes	<130..>233	CDD:223730	45/145 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830