Protein Alignment Nlg3 and nlgn4x

DIOPT Version :10

• Sequence 1: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 909
• Identity: 296/909 - (32%)
• Similarity: 418/909 - (45%)
• Gaps: 211/909 - (23%)

  Fly   152 QLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRF 216
            |....|:.|..|.|.|....|....|.|||.|.|:||||||.|..||.||...:.|:|:|.|.:|
 Frog    42 QAQHPIVPTNYGKIRGTRTPLPIEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIKNATQF 106

  Fly   217 SPVCPQRLPDIHNETAAL-ERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSS 280
            :|||||.|    :|.:.| :.:|......|..::.|:|:|:|||||||||||.:      .|:::
 Frog   107 APVCPQFL----DERSLLNDMLPIWFTANLDTVVSYVQDQNEDCLYLNIYVPTE------DGATT 161

  Fly   281 SSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQ 345
            ...|...::...|........:.           |.||:|::||.||...:||..|||:|||:|.
 Frog   162 KKQADDIANNDRGEDEDIHDPNN-----------KKPVMVYIHGGSYMEGTGNMIDGSILASHGN 215

  Fly   346 ILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGA 410
            ::|:|:||||||||||:.. |:.:|  .||||:|.|.||.|::|||.||||||..:|:.|.|.||
 Frog   216 VIVITVNYRLGVLGFLSTG-DQAAK--GNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGA 277

  Fly   411 ACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLR 475
            :||..|..| ...|| ||.:||:.||:.|:.|::...||||..|:|..|.| ..|....|::|||
 Frog   278 SCVSLLTLS-HYSEG-LFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC-DMLDTIDLVECLR 339

  Fly   476 EKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGI 540
            :|...:|:...|.|..:..||||.|||.||         |..|.
 Frog   340 DKNYKELIQQSITPATYHIAFGPVIDGDVI---------PDDPQ--------------------- 374

  Fly   541 AAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSG--DVQYGIEADRRSRILK 603
                           :||.:   .:...||:|.||.:.|. ..|..|  |.:.|:........:.
 Frog   375 ---------------ILMEQ---GEFLNYDIMLGVNQGEG-LKFVDGMVDNEDGVSLSDFDFSVS 420

  Fly   604 AYVRNTYTF-----HLNEIFATIVNEYTDW---ERPVQHPINIRDETLEAL-SDAQVVAPAAQTV 659
            .:|.|.|.:     .|.|   ||...||||   |.|     ..|.:||.|| :|.|.||||..|.
 Frog   421 NFVDNLYGYPEGKDTLRE---TIKFMYTDWADKENP-----ETRRKTLVALFTDHQWVAPAVATA 477

  Fly   660 DLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEV 724
            |||:.....:|.|.|.:..:....|......||:::||:||.|::|....|..|::|.::.||.|
 Frog   478 DLHARYGSPTYFYAFYHHCQSEMKPTWADSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAV 542

  Fly   725 VMFYWSNFVRTGNPNEQMETE----HGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRA 785
            ||.||:||.:||:||:.:..:    |   .:.:|::.:.|:.|:...:.||:...||::::||||
 Frog   543 VMTYWTNFAKTGDPNKPVPQDTKFIH---TKPNRFEEVAWSKYDPKDQLYLHIGLKPRVRDHYRA 604

  Fly   786 HRLSFWLNLIPDLHK--------------PGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPY 836
            .:::|||.|:|.||.              |..|.....|                .:.:|...|.
 Frog   605 TKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSYPH----------------VTRRPPLKPR 653

  Fly   837 ISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGGKIYPDDMMDGDHAGGAASASQD 901
            |:....|...||                .:...|:|  ..|...|..:|..|
 Frog   654 ITTKRPAMTPAN----------------NAKETQKN--VLGENTIITEDKRD------------- 687

  Fly   902 SDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLS---EPRPQTKLKRQENGQMPNNI 963
                  |||.||||||:|.|||.||:|.||.:||::||.|..   .|.||            .|.
 Frog   688 ------YSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQ------------RNT 734

  Fly   964 CGDL------ETLTIHAKSDPATILSHHH---AMQHHQ----LPPPEFA--------DIPHRAP 1006
            ..|:      |.:::..|.     |.|.|   |:|.|.    ..||::.        |||...|
 Frog   735 TNDIAHIQNEEIMSLQMKQ-----LEHDHECEALQAHDTLRLTCPPDYTLTLRRSPDDIPLMTP 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	231/652 (35%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	231/650 (36%)