Protein Alignment Nlg3 and nlgn3

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 915
• Identity: 303/915 - (33%)
• Similarity: 420/915 - (45%)
• Gaps: 209/915 - (22%)

  Fly   151 AQLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADR 215
            ||:.|:.:||..|.:.|..|.|....|.||:.|.|:|||:||||..||:||.....|||::.|..
 Frog    31 AQVYSQTVNTHYGKLRGTRVPLPSEILGPVDQYLGVPYAAPPVGEKRFLPPEPPPSWSGIRNATH 95

  Fly   216 FSPVCPQRL----PDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDS- 275
            |||||||.:    |||        .||......|..:..|||.|||||||||||||.:...|.|
 Frog    96 FSPVCPQNIQNAVPDI--------MMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISK 152

  Fly   276 ----SGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYD 336
                ..:......|..|:...|...|.:..........:|:.   ||:|::||.||...|||..|
 Frog   153 ECVRKPNKKICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAK---PVMVYIHGGSYMEGSGNMID 214

  Fly   337 GSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSI 401
            ||||||||.::|:|:|||:||||||:.. |:.:|  .||||:|.|.||.|:.||:|.|||||:.|
 Frog   215 GSVLASYGNVVVITLNYRVGVLGFLSTG-DQAAK--GNYGLLDQIQALRWVSENVAFFGGDPHRI 276

  Fly   402 TLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLP 466
            |:.|.|.||:||..|..|.. .|| ||.|||:.|||.|:.|::...|.||..::|..|.| :.|.
 Frog   277 TVFGSGIGASCVSLLTLSHH-SEG-LFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGC-NVLD 338

  Fly   467 HAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQASTAAG 531
            ...::.|||:|:..:|:...|:|..:..||||.|||.||         |..|.
 Frog   339 TVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVI---------PDDPE------------ 382

  Fly   532 NGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAF-FSFNSGDVQYGIEA 595
                                    :||.:   .:...||:|.||.:.|.. |..|..|.:.|:..
 Frog   383 ------------------------ILMEQ---GEFLNYDIMLGVNQGEGLKFVENVVDAEDGVSG 420

  Fly   596 DRRSRILKAYVRNTYTF-----HLNEIFATIVNEYTDW---ERPVQHPINIRDETLEAL-SDAQV 651
            ......:..:|.|.|.:     .|.|   ||...||||   :.|     ..|.:||.|| :|.|.
 Frog   421 SDFDYSVSNFVDNLYGYPEGKDTLRE---TIKFMYTDWADRDNP-----ETRRKTLVALFTDHQW 477

  Fly   652 VAPAAQTVDLHSADHRNSYLYVFDYQTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTK 716
            |.|:..|.|||:.....:|.|.|.:..:....|......||:::||:||.|:||..:.|..|::|
 Frog   478 VEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWADAAHGDEVPYVFGVPMVGPTDLFPCNFSK 542

  Fly   717 TEISLSEVVMFYWSNFVRTGNPNEQMETE----HGSRQERSRYKTIEWTAYESVHKKYLNFDTKP 777
            .::.||.|||.||:||.:||:||:.:..:    |   .:.:|::.:.|:.|....:.||:...||
 Frog   543 NDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIH---TKANRFEEVAWSKYNPRDQLYLHIGLKP 604

  Fly   778 KLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDDEDNNIPSDASVKPLNPPYISRAAN 842
            ::::||||.:::||.:|:|.|            :.|||
 Frog   605 RVRDHYRATKVAFWKHLVPHL------------YNLHD--------------------------- 630

  Fly   843 AAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGGKIYPDDMMDG---DHAGGAASASQDSDG 904
               |.::|..|.:|        |.|...:|.......|:: |....|   ...|..|....:.|.
 Frog   631 ---MFHYTSTTTKV--------PPSDTTQNSHITRRPKVW-DTKRPGVSPTFNGPVAKWDPELDP 683

  Fly   905 F--------AAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQENGQMPN 961
            .        ..|||.||||||:|.|||.||||.||.:||:.||.|       ...:||.:.|.|
 Frog   684 VDPVVIQDPRDYSTELSVTIAVGASLLFLNVLAFAALYYRNDKRR-------QDTQRQPSPQRP- 740

  Fly   962 NICGDLETLTIHAKSDPATILSHHHAMQHHQLPPPEFADIPHRAPPPPKHMKSLQDPGG-----G 1021
                       ....|||                        .:|.||:.:.|||...|     |
 Frog   741 -----------AVTRDPA------------------------HSPVPPEELNSLQINAGHPECEG 770

  Fly  1022 GSVSG 1026
            |.|||
 Frog   771 GGVSG 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	239/662 (36%)
		Aes	<313..>410	CDD:223730	53/96 (55%)
nlgn3	XP_012823589.1	COesterase	31..618	CDD:278561	239/662 (36%)
		Aes	<195..>302	CDD:223730	62/111 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	367	1.000	Domainoid score	I918
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	433	1.000	Inparanoid score	I1667
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D80457at33208
OrthoFinder	1	1.000	-	-		FOG0000662
OrthoInspector	1	1.000	-	-		mtm9495
Panther	1	1.100	-	-	O	PTHR43903
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3146
SonicParanoid	1	1.000	-	-		X375
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100