Protein Alignment Nlg3 and ces3.1

DIOPT Version :9

• Sequence 1: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces3.1 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 650
• Identity: 171/650 - (26%)
• Similarity: 268/650 - (41%)
• Gaps: 142/650 - (21%)

  Fly   157 IINTRNGAISGVIVQLDGRHLDP-VEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVC 220
            ::.|:.|.:.|..|  ..:..|. |..:.|:|:|.||:|.|||..|.....||.|::|...||:|
 Frog    26 LLMTKYGQLLGKTV--GAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSVREATAPSPMC 88

  Fly   221 PQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAG 285
            .|       :...:|.:    .::.|....: ...||||||||::.|
 Frog    89 LQ-------DKEVMELL----ADFFKAKFDF-SRVSEDCLYLNVFTP------------------ 123

  Fly   286 SSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVT 350
                                  |..|.....||:||:||........:.::||.|::|..::||:
 Frog   124 ----------------------ADKGENPGLPVMVFIHGGGLAIGGASMFEGSALSAYENVVVVS 166

  Fly   351 INYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHF 415
            |.||||::|||:...   .::..|:|.:|.:|||.|:::||..|||||.|:|:.|...|...|..
 Frog   167 IQYRLGIMGFLSTGD---KEVRGNFGFLDQVAALQWVRDNIKDFGGDPQSVTIFGESAGGLSVSA 228

  Fly   416 LISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCASDLPHAHLMKCLREKTLD 480
            |:.| .:.|| ||:|||..||..:.|....|...:...::...:| .|....:.|:.||:.||.|
 Frog   229 LVLS-PLSEG-LFHRAIAESGVAILPGLTASKTEEILPLLDMVIN-VSSCSVSDLVGCLKNKTED 290

  Fly   481 QLLSVPIRPPEFGFAFGPS-IDGVVIDGGDYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAG 544
            :::.:   .....:...|: :|||.:       |.|                    .|..:||..
 Frog   291 EIIEI---TAAMRYVIFPAVVDGVFL-------PKP--------------------AEEILAAKE 325

  Fly   545 GWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAY-VRN 608
            ....|..:         .||. ..:..|..||       .|....:.|:|......||.|. :.|
 Frog   326 SHPVPFLI---------GINN-HEFGSMLPVT-------LNITGYREGMEKKDIQAILGALPLLN 373

  Fly   609 TYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNS--YL 671
            |    ::.:...|:.||..   ....|..:|:..|:...|...|.||.:|...    ||:|  .:
 Frog   374 T----VSSVIPFIMEEYFG---DTNDPKELRNNFLDLAGDIIFVIPALRTAKY----HRDSGFPV 427

  Fly   672 YVFDYQTRFGDYPQRQ----GCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNF 732
            |.:::|.|...|...:    ...||::|.::.|.|.:.....|..|.|:.|..||:.:|.||:||
 Frog   428 YFYEFQHRPSLYADSKEDFVKADHGDELYFVGGGPFLKNGILFKSNGTEEEKILSKTIMKYWANF 492

  Fly   733 VRTGNPNEQMETEHGSRQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPD 797
            .|.|:||     .||         ..||..|:. .:.||..:...|.....:..|..||...:||
 Frog   493 ARNGDPN-----GHG---------LAEWPKYDE-DEDYLEINLTQKSSQRLKGERFEFWTITLPD 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	167/642 (26%)
		Aes	<313..>410	CDD:223730	37/96 (39%)
ces3.1	NP_001120019.1	COesterase	25..536	CDD:365897	167/642 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910