Protein Alignment alpha-Est1 and Ces2g

DIOPT Version :10

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 587
• Identity: 176/587 - (29%)
• Similarity: 255/587 - (43%)
• Gaps: 128/587 - (21%)

  Fly    17 LIGHKIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPH 81
            |:||  ||.....:.:.:..|..|||:|........:.....|.|||||:||||.|||..|:.|.
Mouse    20 LLGH--VQGHDSPETSPIRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPE 82

  Fly    82 PWLGVRDCT-YPRAKPMQ--------KHFVLSI--VEGSEDCLYLNVYS-KRLRSDKPLPVIVWI 134
            ||.||||.| .|...|..        |...|::  |..||||||||:|: ...:....|||:|||
Mouse    83 PWSGVRDGTSQPAICPQNVTMNMEGLKELKLTLPPVSMSEDCLYLNIYTPAHAQEGSNLPVMVWI 147

  Fly   135 YGGGFQFGEAGRDFYSPDYF-MQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRW 198
            :||....|.|  ..|..... ..:|||||...||:|.|||.|..|.  ...||.|..|||.||||
Mouse   148 HGGALTVGMA--SMYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDE--HARGNWGFLDQVAALRW 208

  Fly   199 ISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGRWAYR 263
            :.||||.|.|:|..:|:.|||||..||.:.:.:..::||||:|||:||...............|:
Mouse   209 VQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTIFSFSEVVYQ 273

  Fly   264 LACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEE----RRQYVLFPFTPVVEPYITRDC 324
            ...:|  ||.|           |..||...:.:...|:||    .:.:.:.|  .||:...
Mouse   274 TVAKL--SGCE-----------AMDSEALVRCLRGKSEEEILAISKNFQMIP--GVVDGEF---- 319

  Fly   325 VLPRCHREMLPEAWGNDLPLILGGNSFE----------------GLF--SYQSTLHDEEHMLSAF 371
             ||:..:|:|..|..:.:|.|:|.|:.|                |:.  :.|:.|.|     :|.
Mouse   320 -LPKHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSTQTIKGITRENLQAVLKD-----TAP 378

  Fly   372 EVLIPREIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLH-------ILSVKHFWHGIHRT 429
            ::::|.|         ..|||.:..:::.:|....:::|.|.:.       .|.|.:|
Mouse   379 QMMLPPE---------CSDLLMEEYMEDIEDPKTLQIQFTEMMEDFMFVIPSLQVAYF------- 427

  Fly   430 VLARLSHAPATPTYLYRF--------DVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHIL-AN 485
               :.|||   |.|.|.|        ||..||.|             ..|.|::.::|.... ..
Mouse   428 ---QRSHA---PVYFYEFQHQSSFLKDVRPPHVN-------------ADHGDEVPFVFGSFFWGM 473

  Fly   486 KVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLNI---------GKQL 541
            |::.:..|....:|::..|..|||:.|||...:  ..|...|.....:.|||         .::|
Mouse   474 KLNLTEEEKLLNRRMMKYWANFARHGNPNSESL--PYWPVFDHDEQYLQLNIQPAVGQFQKARKL 536

  Fly   542 EF 543
            :|
Mouse   537 QF 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	31..555	CDD:395084	171/573 (30%)
Ces2g	NP_932116.2	COesterase	33..539	CDD:395084	171/572 (30%)