Protein Alignment alpha-Est1 and nlgn3b

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_005165239.1
• Gene: nlgn3b / 567415
• ZFINID: ZDB-GENE-060526-197
• Length: 846
• Species: Danio rerio
• Alignment Length: 618
• Identity: 178/618 - (28%)
• Similarity: 267/618 - (43%)
• Gaps: 129/618 - (20%)

  Fly    35 VCTRDGQVRGHR----RRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCT-YPRA 94
            |.|..|::||.|    ...|...:.|.   |:|:|.|||||.||..|..|..|.|||:.| :|..
Zfish    48 VNTALGRLRGMRVAVATEGLGPVDQYL---GVPYAAPPVGEKRFMPPDAPSAWSGVRNATRFPPV 109

  Fly    95 KPMQ-KHFVLSIV-----------------EGSEDCLYLNVY------SKR-------------- 121
            .|.. ::.|..|:                 |.||||||:|:|      :||
Zfish   110 CPQTVRNAVPDIMMPVWATYNMDTVATYLQEQSEDCLYMNIYVPTQSGTKRTGDMSADTERTEDD 174

  Fly   122 -LRS--DKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDV 183
             ||.  |.|.||:::|:||.:..| .|............:|:|:|.|||||.|||||..|:  ..
Zfish   175 GLRDSRDDPRPVMLFIHGGSYMEG-TGNIMDGSVLASYGNVIVITLNYRVGILGFLSTGDQ--AA 236

  Fly   184 PGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSM 248
            .||.||.||:.|||||::||..|.|||..:||.|...||:.|..|..:..:.||||:||:||||.
Zfish   237 KGNYGLLDQIQALRWINKNIGYFGGDPGRVTVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSA 301

  Fly   249 FCEWA-NEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPF 312
            ...|: |....::...||.::|.:..:.: ::...:||....|:..|.|     :..|.:|  .|
Zfish   302 LSSWSVNYQPVKYTRLLAERVGCNVLDTQ-DLVLCMQKRSYRELVEQEI-----QPARFHV--AF 358

  Fly   313 TPVVEPYITRDCVLPRCHREMLPEAWGNDL--PLILGGNSFEGLFSYQSTLHDEEHMLSA--FEV 373
            .||::..:..|      ..|:|.|. |..|  .::||.|..||....:..:..||..:|.  |:.
Zfish   359 GPVIDGDLIPD------DPEVLMEQ-GEFLNYDIMLGVNQGEGFRFVEGVVEPEEGGVSGSDFDF 416

  Fly   374 LIPREIREKSTQSHLKDLLRQ-FKVDNFDDATRGRMEF-NECLHILSVKHFWHGIHRTVLARLSH 436
            .:...:.........||.||: .|....|.|.|...|. .:.|..:...|.|  :...|:....|
Zfish   417 TVSDFVDSLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVAMFTDHQW--VEPAVVTADLH 479

  Fly   437 AP-ATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLF------------YHILANKVD 488
            |. .:||:.|.|      ::|.:..|....... :|.|:|.|:|            .:...|.:.
Zfish   480 ARYGSPTFFYAF------YHHCQSPMKPPWADS-AHGDELPYVFGVPLIGPTELFPCNFSRNDIM 537

  Fly   489 KSSMEYQTIQRLVGMWVAFARNDNPNCP-------------QIGPTTWEALDEKGP--QMCLNIG 538
            .|::       ::..|..||:..:||.|             :....||.   :.||  |:.|:||
Zfish   538 LSAV-------VMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVTWA---KYGPHDQLYLHIG 592

  Fly   539 KQLEFIVLPESKQNRI--W----DRLYDKNDLF 565
              |:..|....:..::  |    ..||:.:|:|
Zfish   593 --LKPRVRDHYRATKVAFWKHLVPHLYNLHDMF 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	171/586 (29%)
		Aes	<117..>233	CDD:223730	52/138 (38%)
nlgn3b	XP_005165239.1	COesterase	40..609	CDD:278561	173/602 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740