Protein Alignment alpha-Est1 and nlgn3a

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 630
• Identity: 174/630 - (27%)
• Similarity: 271/630 - (43%)
• Gaps: 134/630 - (21%)

  Fly    35 VCTRDGQVRGHRRRTLYDE-----EMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTY--- 91
            |.|:.|::|| .|..|:.|     :.|.   |:|:|.|||||.||..|:||..|.|:::.|:
Zfish    71 VNTQYGKLRG-ARVPLHSEILGPVDQYL---GVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAP 131

  Fly    92 --PR---------AKPMQKHFVLSIV-----EGSEDCLYLNVY---------------------- 118
              |:         ..|:...|.|.||     :.:|||||||:|
Zfish   132 VCPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKIC 196

  Fly   119 ------SKR---------------LRSDKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVV 162
                  ||:               :|.....||:|:|:||.:..| .|............:|:|:
Zfish   197 RKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEG-TGNMIDGSVLASYGNVIVI 260

  Fly   163 TFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHA 227
            |.|:|||.|||||..|:  ...||.||.||:.||||||:||..|.||...|||.|...||:.|..
Zfish   261 TLNFRVGVLGFLSTGDQ--AAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSL 323

  Fly   228 LMTTEQTRGLFHKAIMQSGSMFCEWA-NEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEM 291
            |..:..:.||||:||:||||....|| |....::...||.::|.:..:. .::...|:|..|.|:
Zfish   324 LTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDT-LDMVDCLRKKSAREL 387

  Fly   292 AAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGLFS 356
            ..|.|     :..|.:|.|      .|.|..| |:|.....::.:....:..::||.|..|||..
Zfish   388 VEQDI-----QPARYHVAF------GPVIDGD-VIPDDPEILMEQGEFLNYDIMLGVNQGEGLRF 440

  Fly   357 YQSTLHDEEHML-SAFEVLIPREIREKSTQSHLKDLLRQ-FKVDNFDDATRGRMEF-NECLHILS 418
            .::.:..|:.:. :.|:..:...:.........||.||: .|....|.|.|...|. .:.|..|.
Zfish   441 VENVVDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALF 505

  Fly   419 VKHFWHGIHRTVLARLSHAP-ATPTYLYRFDVDSPHFNHFRQVMCGKHV-RGVSHADDLSYLFYH 481
            ..|.|  :..:|:....||. .:|||.|.|      ::|.:.:|  |.. ...:|.|::.|:|..
Zfish   506 TDHQW--VEPSVVTADLHARYGSPTYFYAF------YHHCQSLM--KPAWSDAAHGDEVPYVFGI 560

  Fly   482 ILANKVD-------KSSMEYQTIQRLVGMWVAFARNDNPNCP-------------QIGPTTWEAL 526
            .:....|       |:.:....:  ::..|..||:..:||.|             :.....|...
Zfish   561 PMIGPTDLFPCNFSKNDIMLSAV--VMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKY 623

  Fly   527 DEKGPQMCLNIGKQLEFIVLPESKQNRI--W----DRLYDKNDLF 565
            :.: .|:.|:||  |:..|....:..::  |    ..||:.:|:|
Zfish   624 NPQ-DQLYLHIG--LKPRVRDHYRATKVAFWKHLVPHLYNLHDMF 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	167/598 (28%)
		Aes	<117..>233	CDD:223730	50/158 (32%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	169/614 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575375
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840