Protein Alignment alpha-Est1 and ces2b

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_021326380.1
• Gene: ces2b / 561967
• ZFINID: ZDB-GENE-041014-96
• Length: 1611
• Species: Danio rerio
• Alignment Length: 603
• Identity: 182/603 - (30%)
• Similarity: 258/603 - (42%)
• Gaps: 108/603 - (17%)

  Fly     5 VGVGDLLKMGTKLIGH-------KIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGI 62
            :|:|...|......|:       |:.|.....|:..||.|:.|.:||........:.:..::.|:
Zfish  1046 LGIGLEQKSSKNFKGNHFHFMIEKLPQIIKEWKEGPVVETKLGSLRGAFLTVKGKDTIVNSYLGV 1110

  Fly    63 PFAQPPVGELRFRAPQPPHPWLGVRDCT-YPRAKPMQKHFVLS----------IVEGSEDCLYLN 116
            |||:||||.||...||....|.||||.| .||....::...::          :.|.||||||||
Zfish  1111 PFAKPPVGPLRLARPQAAEKWQGVRDATKQPRMCLQERQMTVTELEFLSMDVEVPEVSEDCLYLN 1175

  Fly   117 VYS--KRLRSDKPLPVIVWIYGGGFQFGEAGRDFYSPDYF-MQQDVVVVTFNYRVGALGFLSLAD 178
            :|:  |..:.||.|||:|||:|||...|.|  ..|..... ..||||||...||:|.|||||..|
Zfish  1176 IYTPVKPGQGDKKLPVMVWIHGGGLSLGSA--SMYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGD 1238

  Fly   179 RDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIM 243
            .  ..|||.|..|||.||:|:.:||..|.|||.::|:.|||||..||..|:.:....||||:||.
Zfish  1239 E--HAPGNYGFLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIA 1301

  Fly   244 QSGSMFCEWAN----EPSGRWAYRLACQLGYSGSENEK--EVFRYLQKAPASEMAAQGITLVSQE 302
            :||:.|  |..    :|..| |...|.|.....|.:.|  :...:..:..|.|.|
Zfish  1302 ESGTAF--WDGLVMADPFQR-AQTAAKQCNCDSSSSAKIVDCIMHWSEEEALECA---------- 1353

  Fly   303 ERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFE-GLFSYQSTLHDE-- 364
              :::.:..|:..|:.|.     ||:...|::.:...:.:|||.|.|:.| |....:..|..|
Zfish  1354 --KKFQMMHFSVAVDSYF-----LPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWM 1411

  Fly   365 -----EHMLSAFEVLIP----REIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHILSVK 420
                 |.:..|..:..|    |.|.:...:.:|.|.....::........|.:.||
Zfish  1412 NGLKREQIAEALTLTYPDPKDRWIIDLVAKEYLGDTHDPIEIREVYREMMGDVLFN--------- 1467

  Fly   421 HFWHGIHRTVLARLSHAPATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYLFYHILAN 485
                 |....||:.......|.|||...    |...|.|......| ||.|||||    |.|...
Zfish  1468 -----IPALQLAKHHSGTGAPVYLYELQ----HPPSFLQKKRPSFV-GVDHADDL----YFIQGT 1518

  Fly   486 KVDKSSM---------EYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLNI---- 537
            ...|:.:         |.:..:.::..|..||...:||.|  |.|.|...:.:...:.:.:
Zfish  1519 CFAKAHLRISAPFTEEENELCRTVMAYWGNFAHTGSPNGP--GLTHWPEYENENEYLAIGLQQKP 1581

  Fly   538 GKQL-----EFI--VLPE 548
            ||.|     ||:  .|||
Zfish  1582 GKNLKHKHYEFMTKTLPE 1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	170/557 (31%)
		Aes	<117..>233	CDD:223730	56/118 (47%)
ces2b	XP_021326380.1	COesterase	27..539	CDD:306613
		COesterase	553..1065	CDD:306613	4/18 (22%)
		COesterase	1079..1592	CDD:306613	170/561 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820