Protein Alignment alpha-Est1 and nlgn4xa

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 638
• Identity: 171/638 - (26%)
• Similarity: 268/638 - (42%)
• Gaps: 161/638 - (25%)

  Fly    20 HKIVQYRLGT--------------KQTKVVCTRDGQVRGHR----RRTLYDEEMYFAFEGIPFAQ 66
            |.:...||.|              :|..:|.|..|::||.:    ...|...|.|.   |||:|.
Zfish    16 HPLATLRLFTWIVLAAAWLAITWAQQHPIVTTNYGKLRGLKTPLPNEILGPVEQYL---GIPYAL 77

  Fly    67 PPVGELRFRAPQPPHPWLGVRDCT-YPRAKP--MQKHFVLS-----------------IVEGSED 111
            ||.||.||:.|:||..|.|:|:.| :....|  ::..|:|:                 :.:.|||
Zfish    78 PPTGERRFQPPEPPMSWPGIRNATQFAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSED 142

  Fly   112 CLYLNVY---------------------SKRLRSDKPL-PVIVWIYGGGFQFGEAGRDFYSPDYF 154
            |||||:|                     :|.:..:..| ||:|:|:||.:..| .|.........
Zfish   143 CLYLNIYVPTEDVGANKGDDFTNNEGGENKDIHDENGLRPVMVYIHGGSYMEG-TGNMIDGSILA 206

  Fly   155 MQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGES 219
            ...:|:|||.|||:|.|||||..|:  ...||.||.||:.|||||.:||..|.|||:.:|:.|..
Zfish   207 SYGNVIVVTLNYRLGVLGFLSTGDQ--AAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSG 269

  Fly   220 AGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWA-NEPSGRWAYRLACQLGYSGSENEKEVFRYL 283
            |||:.|..|..:..:..||.|||:|||:....|| |....::...||.::|.:..:: .::...|
Zfish   270 AGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRILAEKVGCNMLDS-IDLVECL 333

  Fly   284 QKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILGG 348
            |.....|:..|.||     :.:.::.|      .|.|..| |:|...:.::.:....:..::||.
Zfish   334 QNKNYKELIEQYIT-----QAKYHIAF------GPVIDGD-VIPDDPQILMEQGEFLNYDIMLGV 386

  Fly   349 NSFEGLFSYQSTLHDEEHMLSA--FEVLIPREIREKSTQSHL------KDLLRQ---FKVDNFDD 402
            |..|| |.:...:.|.|..:||  |:..:...:      .||      ||.||:   |...::.|
Zfish   387 NQGEG-FKFVDGIVDSEDGVSANDFDFAVSDFV------DHLYGYPEGKDTLRETIKFMYTDWAD 444

  Fly   403 ----ATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAP-ATPTYLYRFDVDSPHFNHFRQVMC 462
                .||     .:.|..|...|.|  :...|.....||. .:|||.|.|      ::|     |
Zfish   445 KENPETR-----RKTLVALFTDHQW--VAPAVATADLHAQYGSPTYFYAF------YHH-----C 491

  Fly   463 GKHVR----GVSHADDLSYLFYHILANKVD-------KSSMEYQTIQRLVGMWVAFARNDNPNCP 516
            ...::    ..:|.|::.|:|...:....|       |:.:....:  ::..|..||:..:||.|
Zfish   492 QSEMKPSWSDSAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAV--VMTYWTNFAKTGDPNQP 554

  Fly   517 QIGPTTWEALDEKGPQMCLNIGKQLEFIVLPESKQNRI----WDRLYDKNDLF 565
                                :.:..:||   .:|.||.    |.:...|:.|:
Zfish   555 --------------------VPQDTKFI---HTKPNRFEEVAWSKYNPKDQLY 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	160/600 (27%)
		Aes	<117..>233	CDD:223730	49/137 (36%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:306613	166/611 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740