Protein Alignment alpha-Est1 and ces3

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001038401.1
• Gene: ces3 / 560651
• ZFINID: ZDB-GENE-030131-9563
• Length: 549
• Species: Danio rerio
• Alignment Length: 554
• Identity: 158/554 - (28%)
• Similarity: 234/554 - (42%)
• Gaps: 108/554 - (19%)

  Fly    34 VVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCTYPRAKPMQ 98
            ||..:.|.|||...:......:...:.||||||||||..|..||||...|.|:|:.|...:..:|
Zfish    28 VVVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPVQGWEGIRNATEYSSMCLQ 92

  Fly    99 ---------KHFVLSI--VEGSEDCLYLNVY--SKRLRSDKPLPVIVWIYGGGFQFGEAGRDFYS 150
                     |...|.:  ...||||||||||  |:|..||| .||:|||:||....|.|.....:
Zfish    93 DPNIVPKYAKSMTLELPPTGVSEDCLYLNVYTPSQRSESDK-FPVMVWIHGGALVIGGACMYDGT 156

  Fly   151 PDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITV 215
            | ....:.||||...||:|.||:||..|:  ...||.|..||:.||:|:.|||..|.||||::|:
Zfish   157 P-LAAYEKVVVVVIQYRLGILGYLSTGDQ--HAQGNWGFLDQIAALQWVQQNIEAFGGDPQSVTI 218

  Fly   216 MGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCE-WANEPSGRWAYRLA--CQLGYSGSE--- 274
            .|||||..|...|..:..|:|||.:||.|||....: ::.:....:|..:|  .:..:|.||
Zfish   219 AGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYSFKDPLTYAKVIANITECDFSSSEVLV 283

  Fly   275 ------NEKEVFRYLQK---APASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCH 330
                  .|:::.:..||   .|.:.:..:.|. ...||..:...||..|::......:......|
Zfish   284 KCIREMTEEQIIKAAQKKYRLPGATVDGEFIK-AQPEEILKSKDFPKIPILVGTTNHEFGWTLSH 347

  Fly   331 REMLPEAWGN-----------DLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKST 384
             .:||:.|..           |.....|.:...|:.:       :|:..:|   ..|.|||:..|
Zfish   348 -AILPKDWAKGMDAKSAKQTLDFFYNAGASEANGIIA-------DEYFKNA---KTPEEIRDAFT 401

  Fly   385 QSHLKDLLRQFKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAPATPTYLYRFDV 449
            :. |.|::                     :.|.|:|          :|........|.|:|.|..
Zfish   402 EL-LGDII---------------------MVIPSIK----------VASYHRDAGAPVYMYEFQH 434

  Fly   450 DSPHFNHFRQVMCGKHVRGVSHADDLSYLF--------YHILANKVDKSSMEYQTIQRLVGMWVA 506
            .....|.||.    ..|: ..|.|::.::|        ..:.....::.:...:|:.:   .|..
Zfish   435 GPSIANKFRP----SFVK-ADHGDEIGFMFGACFWDGQVKVTGTLTEEENQLCRTVMK---YWAN 491

  Fly   507 FARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQ 540
            |.|..:|| |  .|..|...|:....  ||:|.|
Zfish   492 FVRTGSPN-P--APVPWPVYDQSNKY--LNLGLQ 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	158/554 (29%)
		Aes	<117..>233	CDD:223730	53/117 (45%)
ces3	NP_001038401.1	COesterase	24..535	CDD:278561	158/554 (29%)
		Aes	<122..>235	CDD:223730	53/116 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575337
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740