Protein Alignment alpha-Est1 and Ces2h

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 554
• Identity: 167/554 - (30%)
• Similarity: 251/554 - (45%)
• Gaps: 82/554 - (14%)

  Fly    37 TRDGQVRG---HRRRTLYDEEM-YFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCT-YP---- 92
            |..||:.|   |.:    |.:: ..:|.|||||:||||.|||..|:||.||.||||.| :|
Mouse    35 THTGQILGSLIHMK----DLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCL 95

  Fly    93 ---RAKPMQKHFVLSIV----EGSEDCLYLNVYS-KRLRSDKPLPVIVWIYGGGFQFGEAGRDFY 149
               .|..||...:|.:.    ..||||||||:|: ........|||:|||:||....|.|  ..|
Mouse    96 QDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMA--SMY 158

  Fly   150 SPDYF-MQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNI 213
            ..... ..::|||||..||:|.|||.|..|.  ...||.|..|||.||||:.||||.|.|:|..:
Mouse   159 DGSMLAAMENVVVVTIQYRLGVLGFFSTGDE--RARGNWGYLDQVAALRWLQQNIAYFGGNPDRV 221

  Fly   214 TVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGRWAYRLACQLGYSGSENEKE 278
            |:.|.|||..||.:|:.:..::|||..|||:||..........|....|:....|  ||.|...
Mouse   222 TIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQTVANL--SGCEQVD- 283

  Fly   279 VFRYLQKAPASEMAAQGITLVSQEE----RRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWG 339
                      ||.....:...|:||    .:.:.:.       |.|.....|||..:|::..|..
Mouse   284 ----------SEALVNCLRGKSEEEIMAINKAFKII-------PGIVDGIFLPRHPQELMASADF 331

  Fly   340 NDLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKSTQ----SHLKDLLRQFKVDNF 400
            :.:|.|:|.|:.|..:...|::...:........::...::.::||    ..:.|||.:..:.:.
Mouse   332 HPVPSIIGVNNDEYGWIIPSSMSMIDSKKGMDRQMVQAILQRRATQMMWPPEVSDLLMEEYMGDN 396

  Fly   401 DDATRGRMEFNECLHILSVKHFWHGIHRTVLARL--SHAPATPTYLYRFDVDSPHFNHFRQVMCG 463
            :|....:::|.|.:     |.|...|....:|:.  |||   |.:.|.|.    |...|.:....
Mouse   397 EDPQFLQVQFKEMM-----KDFTFVIPALQVAQFQRSHA---PVFFYEFQ----HRPSFFKDSKP 449

  Fly   464 KHVRGVSHADDLSYLFYHIL-ANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALD 527
            .||: ..|.|::.::|.... ..:||.:..|....:|::..|..|||..|||..  |...|...|
Mouse   450 SHVK-ADHGDEILFIFRSFWGGTQVDFTEEEELLSRRMMKYWANFARQRNPNSE--GLPYWPMFD 511

  Fly   528 EKGPQMCLN----IGKQLEFIVLPESKQNRIWDR 557
            :....:.|:    :|:.|      ::::.:.|.:
Mouse   512 QDEQYLQLDTQPAVGRAL------KTRRLQFWTK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	165/536 (31%)
		Aes	<117..>233	CDD:223730	50/117 (43%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	166/550 (30%)
		Aes	<127..>230	CDD:223730	46/106 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832872
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640