Protein Alignment alpha-Est1 and alpha-Est7

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 260/581 - (44%)
• Similarity: 354/581 - (60%)
• Gaps: 33/581 - (5%)

  Fly     1 MEIRVGVGDLLKMGTKLIGHKIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFA 65
            |...:|..:.|:...|.|.||:.|||..|.:|.|..|..|||||.:|.:|||.. ||:|||||:|
  Fly     1 MNKNLGFVERLRWRLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDVP-YFSFEGIPYA 64

  Fly    66 QPPVGELRFRAPQPPHPWLGVRDCTYPRAKPMQKHFVLSIVEGSEDCLYLNVYSKRLRSDKPLPV 130
            |||||||||:|||.|.||..||||:.|:.|.:|..||...|||||||||||||:..::.||..||
  Fly    65 QPPVGELRFKAPQRPIPWERVRDCSQPKDKAVQVQFVFDKVEGSEDCLYLNVYTNNVKPDKARPV 129

  Fly   131 IVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMA 195
            :|||:||||..|||.|::|.|||||::|||:||..||:|||||:||...:|:|||||||||||:|
  Fly   130 MVWIHGGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLA 194

  Fly   196 LRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWA-NEPSGR 259
            |:||..|.|.|.|||..|||.|||||.||.|.:|.|:||:||||:.|:||||..|.|| |.....
  Fly   195 LKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITH 259

  Fly   260 WAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDC 324
            ..||:|..:||.|.:|:|:|..:||...|.::......:::.|||...::|.|.|.:||:.|.:|
  Fly   260 NPYRIAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPEC 324

  Fly   325 VLPRCHREMLPEAWGNDLPLILGGNSFEGLFSYQST--LHDEEHMLSAFEVLIPREI------RE 381
            |:.:..:||:..||.|.:|:.:|..|:|||......  :......|.|....||:|:      :|
  Fly   325 VISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKE 389

  Fly   382 K--STQSHLKDLLR---QFKVDNFDDATRGRMEFNECLHILSVKHFWHGIHRTVLARLSHAPATP 441
            |  |..:.::|:.|   :...||:.|             :.|:.:|.....|.|.:|.::|...|
  Fly   390 KLDSWSAQIRDVHRTGSESTPDNYMD-------------LCSIYYFVFPALRVVHSRHAYAAGAP 441

  Fly   442 TYLYRFDVDSPHFNH-FRQVMCGKHVRGVSHADDLSYLFYHILANKVDKSSMEYQTIQRLVGMWV 505
            .|.||:|.||..... :|.:..|:.|:||||||||||.|..:||.::.|.|.||:.|:|.||:|.
  Fly   442 VYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWT 506

  Fly   506 AFARNDNPNCPQIGPTTWEALD--EKGPQM--CLNIGKQLEFIVLPESKQNRIWDRLYDKN 562
            .||...||...:|.......:|  .|..::  ||||...|:||.|||..:.::|:.|||.|
  Fly   507 QFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLKVWESLYDDN 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	239/531 (45%)
		Aes	<117..>233	CDD:223730	72/115 (63%)
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	230/500 (46%)
		Aes	<116..>221	CDD:223730	66/104 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467349
Domainoid	1	1.000	450	1.000	Domainoid score	I1603
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	492	1.000	Inparanoid score	I3113
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26273
OrthoDB	1	1.010	-	-		D18817at7147
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	12	11.810