Protein Alignment alpha-Est1 and CG5397

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001259865.1
• Gene: CG5397 / 33313
• FlyBaseID: FBgn0031327
• Length: 665
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 144/652 - (22%)
• Similarity: 245/652 - (37%)
• Gaps: 192/652 - (29%)

  Fly    20 HKIVQYRLGTKQTKV-----------VCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELR 73
            |..|:..:|.||:|.           :..||.:|.|.|.    .....::|.|:.:|:||||.||
  Fly    30 HVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRN----PSTGIYSFLGMHYAEPPVGPLR 90

  Fly    74 FRAP--------------QPPHPWLGVRDCTYPRAKPMQKHFVLSIVEGSEDCLYLNVYSKRLRS 124
            :..|              .||        |..|..:..|:      :.|.||||.||||:.::..
  Fly    91 YSRPVYKRLAGDFNATKHGPP--------CIQPHPQFPQR------IIGDEDCLLLNVYTPQMPD 141

  Fly   125 DKP-LPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAG 188
            :.. |||.|||:.||:::|.|.:  |......|:..:||...||:|:||.:....:..|  ||..
  Fly   142 ETTGLPVFVWIHPGGYRYGSAAQ--YDATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFD--GNLA 202

  Fly   189 LKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVH--ALMTTEQTRGLFHKAIMQSGSMFCE 251
            :.|...||||::..|:.|.|:|:.:..:|..:||||..  ::..|.::.|..|..:..||:...:
  Fly   203 MFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQ 267

  Fly   252 WANEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEM----------------AAQGIT--- 297
            :|.:.....:.:...::....:.||.|:...|:...|.::                ..:|:|
  Fly   268 YAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNV 332

  Fly   298 -----LVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREMLPEAWGNDLPLILG------GNS- 350
                 :.|:::.|   ..|...|.||            .:.|..:..:.:||:.|      .||
  Fly   333 GFQPHIESEDDGR---ALPSLIVGEP------------EQQLKSSNFSGIPLLTGVTKHETANSV 382

  Fly   351 ----FEGLF----SYQSTLHDEEHMLSAF-------------------EVLIPREIREKSTQSHL 388
                .|.:|    .:..:|.|..:.|::|                   .||.|.          |
  Fly   383 TVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPT----------L 437

  Fly   389 KDLLRQFKVDNFDDATRGRME------FNECLHILSVKHFWHGIHRTVLARLSHAPATPTYLYRF 447
            :|:.:..:..|.|......:|      ||  |..:.....|        :||:     |.::|.|
  Fly   438 QDVWKVPQALNVDQVLSKVVESTTDVLFN--LPAVLTTQVW--------SRLA-----PAFMYSF 487

  Fly   448 DVD---SPHFNHFRQVMCGKHV-----RGVSHADDLSYLF--YHILANKVDK----SSMEYQTIQ 498
            :.:   |...|..:.:......     ..|.|.|::.|:|  ..|..|.:::    |:.:.:...
  Fly   488 EYNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRN 552

  Fly   499 RLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQMCLN--IGKQLEFIVLPESKQNRIWDRLYDK 561
            .|:.:.|.||..|.              :|.|......  .||...||        :|..:|...
  Fly   553 NLIDLLVKFANKDK--------------EEGGKSSIFQSVTGKATPFI--------KIDTKLQTS 595

  Fly   562 ND 563
            ||
  Fly   596 ND 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	136/620 (22%)
		Aes	<117..>233	CDD:223730	39/118 (33%)
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	136/620 (22%)
		Aes	82..>261	CDD:223730	61/196 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	5	4.810