Protein Alignment alpha-Est1 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 147/610 - (24%)
• Similarity: 233/610 - (38%)
• Gaps: 139/610 - (22%)

  Fly    16 KLIGHKIVQYRLGTKQTKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPP 80
            |.|..|::......:..||:.|..|:|||....: .|....:.|:.:|||:||:|:|||..||.|
 Worm     5 KFILFKLILLFPDIQSLKVIETSYGRVRGITEWS-DDNNHKYMFKSVPFAKPPIGKLRFAPPQYP 68

  Fly    81 HPWLGVRDCT-YPRA--------KPMQKHFVLSIVEGSEDCLYLNVYS--KRLRSDKPLPVIVWI 134
            ..|.||.|.: |..|        ...|:|.       ||||||:|:::  |.|||  ...|||:.
 Worm    69 DSWSGVLDASKYSPACLSNSSTTSTPQEHV-------SEDCLYINIFTSEKCLRS--KCAVIVYF 124

  Fly   135 YGGGFQFGEAGRDFYSPDYF-----MQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVM 194
            :||.:. |::...|  ||.|     :.:||::.....|:|..|.|......| :..|..:.|.|.
 Worm   125 HGGAYN-GDSATMF--PDNFILERYVAEDVILAIPGVRLGVFGQLYFGPSAL-LTENLFMFDAVQ 185

  Fly   195 ALRWISQNIAQFNGDPQNITVMGESAGAASVHAL---MTTEQTRGLFHKAIMQSGS---MFCEWA 253
            ||.::...|..|.|||:.:|:||.|:|...|.||   .:.:....||.:.|:.||:   .|.:..
 Worm   186 ALDFVHNEIPNFGGDPKQVTIMGHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYDLL 250

  Fly   254 NEPSGRWAYRLACQLGYSGSENEK------EVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPF 312
            .:.|...:.:|.|   ::|::.|:      |:...:::....|:...      |:.........|
 Worm   251 VDNSFIISEKLGC---FNGTQEERTDANIAEILECMRQIDGHEIVGM------QKHMEDVYKLTF 306

  Fly   313 TPVVE--PYITRDCVLPRCHREMLPEAWGNDLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLI 375
            ..::.  |::..:..:.:......|.            |:..|...|:.. ::.|..|......:
 Worm   307 KSLLRGAPFMELNGKIEKFRNSTSPR------------NAIFGTTEYEFR-NEVERYLYITTTFL 358

  Fly   376 PREIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNECLHI-LSVKHFWHGIHRTVLARLSHAPA 439
            ..| ...:...|..|.|.|    |.|....|     :.:.| :|...|        .:.:::|.|
 Worm   359 DFE-NPVAVAQHFDDELMQ----NMDTMING-----DAVSIFVSAAAF--------SSAMANAGA 405

  Fly   440 ------TPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSHADDLSYL--FYHILA------------ 484
                  |..:.|.|.|..      .|...|.| |.|.|..|:..|  ||..|.
 Worm   406 DVYLFETRQWPYSFHVSD------MQYFIGIH-REVLHTHDMDILDSFYSKLLVNFTKTGAPSPE 463

  Fly   485 -NKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEK------GPQMCL--NIGKQ 540
             |.::...|.|..:           |.|..|..  ||...|...:|      |..|..  ||.|.
 Worm   464 WNSLEPEKMNYLEL-----------RVDTRNGK--GPVMLEGYHDKEVSFWYGDMMDYDRNITKM 515

  Fly   541 LEFIVLPESKQN-----RIWDRLYD 560
            .:...||...|.     :.|..:.:
 Worm   516 RQSKGLPRENQGVESQLKYWSSIVE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	140/572 (24%)
		Aes	<117..>233	CDD:223730	39/125 (31%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	135/555 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157176
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740