Protein Alignment alpha-Est1 and cest-9.1

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 140/558 - (25%)
• Similarity: 217/558 - (38%)
• Gaps: 118/558 - (21%)

  Fly    33 KVVCTRDGQVRGHRRRTLY--DEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCT-YPRA 94
            ||:.|..|::||   .|::  |:...:.|:.:|||:||||.|||..||.|..|.|:.|.: |..|
 Worm    19 KVIQTSYGKLRG---ITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKYSPA 80

  Fly    95 --------KPMQKHFVLSIVEGSEDCLYLNVYSKRLRSDKPLPVIVWIYGGGFQFGEA--GRDFY 149
                    ...|||:       ||||||:|:::.....:...||||:.:||.:....|  ..|.:
 Worm    81 CMSNSSSTSTPQKHY-------SEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSAIMFNDTF 138

  Fly   150 SPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNIT 214
            ..|.:..:|||.|....|:|..|.|.....|| :..|..|.|.|.||.::...|..|.||.:.:|
 Worm   139 ILDRYAAEDVVFVIPAVRLGVFGQLYFGPSDL-LSENLFLYDAVQALSFVHSEINYFGGDSKRVT 202

  Fly   215 VMGESAGAASVHAL---MTTEQTRGLFHKAIMQSGS---MFCEWANEPSGRWAYRLACQLGYSGS 273
            .||.|:|...|.||   ...:....||.:.|:.|.:   .|.:...:.|.....:..|   |:|:
 Worm   203 AMGHSSGGTIVDALGFSKLIDPGVKLFQQMIVLSATGMFGFYDMVVDNSFAIVEKFGC---YNGT 264

  Fly   274 ENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREML---- 334
            ::::      ..|..:||.                              ||:.....||||
 Worm   265 KDDR------PNANIAEML------------------------------DCMRQIDGREMLLMQR 293

  Fly   335 --PEAWGNDLPLILGGNSFEGLFSYQSTLHDEEHMLSAFEVLIPREIREKSTQSHLKDLLRQFKV 397
              .|....|...:|.|..|   ......:.|.:....:..:|......|.....|:...:....:
 Worm   294 HMEEVDDRDFRSVLRGAPF---LESNGKIADLKKSPPSRNLLYGTTEHEFRNVDHMNPYISGIFL 355

  Fly   398 DNFDDATRGRMEFNECLHILSVKHFWHGIHRTVL---ARLSHAPA-TPTYLYRFDV-DSPHFNHF 457
            | ||:.......::|.| :.:::...:|....:.   :..|.|.| |...:|.|:. ..|:..|.
 Worm   356 D-FDNPVAVARYYDEQL-MANLETMINGDAAAIFICASTFSTAMANTGADVYLFETRQKPYSFHV 418

  Fly   458 --RQVMCGKHVRGVSHADDLSYL--FY-HILAN------------KVDKSSMEYQTIQRLVGMWV 505
              .|...|.| |.:.|..|:..|  || .:|.|            .:|...|.|..::....|
 Worm   419 SDMQYFVGIH-REIYHRPDMDILDTFYSKLLVNFTKMGVPSPEWAPLDPERMNYLELKVDSDM-- 480

  Fly   506 AFARNDNPNCPQIGPTTWEALDEKGPQMCLNIGKQLEF 543
                       :.||...|...||  :|.|..|:.:||
 Worm   481 -----------KEGPVMLEGFHEK--EMELWFGEMMEF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	138/554 (25%)
		Aes	<117..>233	CDD:223730	37/120 (31%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	136/549 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740