Protein Alignment alpha-Est1 and cest-26

DIOPT Version :10

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 167/576 - (28%)
• Similarity: 268/576 - (46%)
• Gaps: 87/576 - (15%)

  Fly    32 TKVVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDCT-----Y 91
            :|.|.||:|.|.|.|.:...|.|:.. |.|||||:.|||:|||:.|:....|.||:.|.     .
 Worm    41 SKQVRTRNGLVEGFRIKIDDDREVDM-FLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRA 104

  Fly    92 PRAKPMQKHFVLSIVEGSEDCLYLNVYSKRLRSDKPL----PVIVWIYGGGF------QFGEAGR 146
            |:|....:.|.|.:.: |||||||||:|...::::..    ||:|:::||||      ::|:.|
 Worm   105 PQADFFWERFTLGVGK-SEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEG- 167

  Fly   147 DFYSPDYFMQQDVVVVTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQ 211
               ...|..:..|||||..||:|.|||.|..|:  ..|||.||.|..|||:|:..|:..|.|||:
 Worm   168 ---IAKYLCRHGVVVVTIQYRLGLLGFFSTGDQ--VCPGNLGLWDMTMALQWVRDNVHAFGGDPR 227

  Fly   212 NITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEWANEPSGR-------WAYRLACQLG 269
            .:||.|:|||..||..|..:..:|.|||:.:..:|:..|||:.....|       :|||......
 Worm   228 KVTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNACREFAYRKCWDEK 292

  Fly   270 YSGSENEKE-VFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPVV--EPYITRDCVLPRCHR 331
            .:..||..| :..:|:.....|...:.:|....:..:  :.....||:  :|    ...||:...
 Worm   293 QARDENASESMLEFLRTRKEREFEKRLLTRKGVDVSK--IGLDLAPVIGSKP----SDFLPKSIE 351

  Fly   332 EMLPEAWGNDLPLILGGNSFEGLF--SYQSTLHDEEHMLSAFEVLIPRE-------IREKSTQSH 387
            |:..||...:  :::|....|||.  |...:..||:.:.....:||..|       :||::.:.:
 Worm   352 ELRKEAPKKN--IMVGTCEHEGLLFASLGPSNFDEKGIDKLLALLITEENHEDFEALREEAKKMY 414

  Fly   388 LKDLLRQFKVDNFDD---ATRGRMEFNECLHILSVKHFWHGIHRTV--LARLSHAPATPTYLYRF 447
            ||.|     .|:.||   |.||.::....|.:.      :|.:...  :.:|.:    ..::|.|
 Worm   415 LKKL-----SDDEDDKEVAARGYIQLYSDLFVN------NGTYNYAEKMTKLGN----KVFMYSF 464

  Fly   448 DVDSPHFNHFRQVMCGKHVRGVSHADDLSYLF-----YHILANKVDKSSMEYQTIQRLVGMWVAF 507
            |..:|  ..|..:......|..:|..:|:|:|     ::...|:.|::.::..|     .||..|
 Worm   465 DYCNP--RSFGILSLRAPFRAATHCTELAYIFGVSIVFNYRYNESDRAMLDLMT-----KMWTNF 522

  Fly   508 ARNDNPNCPQIGPTT----WEALDEKGPQMCLNIG-KQLEFIVLPESKQNRIWDRL 558
            |:..|||......|.    ||...::.|...|.|. |:.|...:.:..:...|.::
 Worm   523 AKYGNPNGQYEDSTVFDFKWEPTSKEEPTNFLAINEKKCEMQTVYQDNRAEFWKKI 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	31..555	CDD:395084	166/571 (29%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	166/571 (29%)