Protein Alignment alpha-Est1 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 156/554 - (28%)
• Similarity: 241/554 - (43%)
• Gaps: 117/554 - (21%)

  Fly    30 KQTKVVCTRDGQVRGHRRRTLYD--EEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVRDC-TY 91
            |.|:|.....|.:||:    :|:  :::...:.|||||:.|:|:|||:.......|....|| .|
 Worm    12 KNTEVFNASCGPIRGN----VYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKY 72

  Fly    92 PRAKPMQKHFVLSIVE-------GSEDCLYLNVYSKRLRS---DKPLPVIVWIYGGGFQFGEAGR 146
            ....|........:|.       ..::||.|||::.:.:|   ....||:|:.|||||:.|
 Worm    73 GPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVG---- 133

  Fly   147 DFYS--PDYFMQ-----QDVVVVTFNYRVGALGFLSLADRDLDVP-GNAGLKDQVMALRWISQNI 203
             |.|  .||.:.     :||::||.|||:|.|||.:..|   ||. ||.||.||.:||:|:.::|
 Worm   134 -FSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGD---DVARGNWGLWDQALALQWVQKHI 194

  Fly   204 AQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFCEW---ANEPSGRWAYRLA 265
            ..|.|||.|:|:.|.|||.|||..|..:......|.|.|..||:..|.:   :.:..|......|
 Worm   195 KSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFA 259

  Fly   266 CQLGYSGSEN----------EKEVFRYLQ--KAPASEMAAQGITLVSQEERRQYVLFPFTPVVEP 318
            ...||:|:::          :.|:|...:  |.|||.|                  |.|.|..:
 Worm   260 NHHGYTGNDSKSLLQWYQSQDSEIFLKAEGYKCPASGM------------------FSFVPNFD- 305

  Fly   319 YITRDCVLPRCHREMLPEAWGNDLPLILG---GNSFEGLFSYQSTLHDEEHMLSAF---EVLIPR 377
                ....|:...|:..||......:.:|   |..||..::.|.|   .:.||||.   ||:..|
 Worm   306 ----GDFFPKPFDELRKEAPKLGAIVSIGEYEGLGFEDFYAGQKT---PQQMLSAALGPEVVRNR 363

  Fly   378 -EIREKSTQSHLKDLLRQFKVDNFDDATRGRMEFNE-----CLHILSVKHFWHGIHRTVLARLSH 436
             |:.:::.:|:||:               |..|..|     .:.|....:|..|...||.:.:.:
 Worm   364 EEVVKRAAESYLKN---------------GGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKY 413

  Fly   437 APATPTYLYRFDVDSPHFNHFRQVMCGKH--VRGVSHADDLSYLFYHILANKVDKSSMEYQTIQR 499
              ....|||.|:    :||....::.||:  ....:|..||.|:|    .....:.|.|.:.:..
 Worm   414 --GNTVYLYSFN----YFNPNTPIVFGKNRPFNAANHGSDLRYIF----GEGTGEFSKEDRQVMD 468

  Fly   500 LVGMW-VAFARNDNPNCPQIGPTTWE--ALDEKG 530
            ::|.: ..||:..|||...:. ..||  :||..|
 Worm   469 MMGTYHTNFAKYGNPNGKGVS-VPWEKYSLDNPG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est1	NP_524269.3	COesterase	28..541	CDD:278561	156/554 (28%)
		Aes	<117..>233	CDD:223730	53/126 (42%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	155/552 (28%)
		Aes	<105..>239	CDD:223730	58/141 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650